Aminotransferases
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Overview
- Aminotransferases act as catalysts in chemical reactions in the cells, where an amino group is transferred from a donor molecule to a recipient molecule
- An underlying disease pathology is present when aminotransferases appear in the blood stream
- Aminotransferases serve as diagnostic tools for liver, bile ducts, muscles, skeleton, and heart
- The tow most sensitive aminotransferases are:
Reference Range
| Alanine Aminotransferase (ALT) | 0-23 U/l |
| Aspartate Aminotransferase (AST) | 0-19 U/l |
Differential Diagnosis
Differential Diagnosis
Increased Aminotransferases
- Acute hepatitis
- Alcoholic hepatopathy
- Cholangitis
- Cholestasis
- Chronic active hepatitis
- Cirrhosis
- Dermatomyositis
- Drugs
- Epstein-Barr Virus
- Fatty liver
- Hepatic tumor
- Hypothyroid myopathy
- Malignant hyperthermia
- Malignancy
- Myocardial Infarction
- Myositis
- Open heart surgery
- Perimyocarditis
- Polymyositis
- Primary biliary cirrhosis
- Progressive myodystrophia
- Pulmonary Embolism
- Renal infarction
- Seizure
- Severe muscle trauma
- Spasms, muscle injuries
- Strong physical work [1] [2]
References
References
Acknowledgements
Acknowledgements
The content on this page was first contributed by Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
List of contributors:
Suggested Reading and Key General References
Suggested Reading and Key General References
Suggested Links and Web Resources
Suggested Links and Web Resources
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