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Anisopoikolcytosis

Introduction

Overview

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Overview

Poikilocytosis refers to the presence in the blood of poikilocytes. Poikilocytes are abnormally shaped red blood cells as seen on a blood film. Rather than being seen as a sign of any one disease, poikilocytosis is a rather general condition. There may, however be a predominance of one particular type of abnormally shaped red cells, some of which may indicate possible presence of a specific disease or disorder. [2]

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

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Overview

Pathology

Teardrop cells (dacrocytes – myelofibrosis)[1]

References

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Causes

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Overview

Causes

Abnormal red blood cells are seen in a wide range of conditions, so poikilocytosis is not specific. However, specific types of poikilocytes may be seen in particular disease states and/or disorders.

Membrane Abnormalities

  1. Acanthocytes or Spur/Spike cells
  2. Codocytes or Target cells
  3. Echinocytes and Burr cells
  4. Elliptocytes and Ovalocytes
  5. Spherocytes
  6. Stomatocytes or Mouth cells

Trauma

  1. Dacrocytes or Teardrop Cells
  2. Keratocytes
  3. Microspherocytes and Pyropoikilocytes
  4. Schistocytes
  5. Semilunar bodies

References

Risk Factors

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References

Natural History, Complications and Prognosis

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References

Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy

Case Studies

Case Studies

Case #1

Related Chapters

Template:Abnormal clinical and laboratory findings Template:SIB


Template:WikiDoc Sources

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]