Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Anti-streptolysin O titer
Introduction
Antistreptolysin O titre (AS(L)O titre or AS(L)OT) – titre of (serum) antistreptolysin O antibodies; a blood test used to assist in the diagnosis of a streptococcal infection or indicate a past exposure to streptococci.
The ASOT helps direct the antimicrobial treatment and is used to assist in the diagnosis of scarlet fever, rheumatic fever and post infectious glomerulonephritis.
A positive test usually is >200 units/mL,[1] but normal ranges vary from laboratory to laboratory and by age.[2]
The false negatives rate is 20-30%.[1] If a false negative is suspected then an anti-DNase B titre should be sought. False positives can result from liver disease and tuberculosis.[1]
References
References
- ↑ 1.0 1.1 1.2 Antistreptococcal antibody titres. gpnotebook. URL: http://www.gpnotebook.co.uk/cache/-1630535637.htm. Accessed on: March 31, 2007.
- ↑ Danchin M, Carlin J, Devenish W, Nolan T, Carapetis J (2005). “New normal ranges of antistreptolysin O and antideoxyribonuclease B titres for Australian children”. J Paediatr Child Health. 41 (11): 583–6. PMID 16398843.
External links
External links
- Antistreptococcal antibody titres – GPnotebook.co.uk.
- Antistreptolysin O Titer – medterms.com.
- Antistreptolysin O Titer, Serum
- Streptococcal antibody tests – healthAtoZ.com
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]