
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Antimicrosomal antibodies
Introduction
Synonyms and Related Keywords: Thyroid antimicrosomal antibody; Antimicrosomal antibody; Microsomal antibody; Thyroid peroxidase antibody; TPOAb
Overview
Overview
Antithyroid microsomal antibody is a test to measure antithyroid microsomal antibodies in the blood. Microsomes are found inside thyroid cells. The body produces antibodies to microsomes when there has been damage to thyroid cells. [1] [2] [3]
Differential diagnoses
Differential diagnoses
A negative test is normal. A positive test may be due to:
- Autoimmune hemolytic anemia
- Granulomatous thyroiditis
- Hashimoto’s thyroiditis
- Nontoxic nodular goiter
- Rheumatoid arthritis
- Sjogren syndrome
- Systemic lupus erythematosus
- Thyroid cancer
High levels of these antibodies have also been linked to an increased risk of:
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
References
References
- ↑ Mecacci F, Parretti E, Cioni R, et al. Thyroid autoimmunity and its association with non-organ-specific antibodies and subclinical alterations of thyroid function in women with a history of pregnancy loss or preeclampsia. J Reprod Immunol. 2000 Feb;46(1):39-50.
- ↑ Vaquero E, Lazzarin N, De Carolis C, Valensise H, Moretti C, Ramanini C. Mild thyroid abnormalities and recurrent spontaneous abortion: diagnostic and therapeutical approach. Am J Reprod Immunol. 2000 Apr;43(4):204-8.
- ↑ Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
