Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Bazin disease
Introduction
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Synonyms and keywords: Erythema induratum; nodular vasculitis
Overview
Overview
Bazin disease is a skin ulceration on the back of the calves. It was formerly thought to be a reaction to the tuberculum bacillus. It is very rare now.
Historical Perspective
Bazin disease is named for Pierre-Antoine-Ernest Bazin.[1][2]
Pathophysiology
Bazin disease is a type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis.
Causes
Bazin disease was formerly thought to be a reaction to tuberculum bacillus, but it is now considered a panniculitis that is not associated with a single defined pathogen. [3]
Epidemiology and Demographics
Bazin disease is seen most commonly in adolescent and menopausal women.
Risk Factors
Bazin disease is initiated or exacerbated by cold weather.
Diagnosis
History and Symptoms
50% of patients will have a past or present history of tuberculosis at extracutaneous site. Patients typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves.
Physical Examination
Patients typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves.
References
- ↑ Template:WhoNamedIt
- ↑ P. A. E. Bazin. Leçons théoriques et cliniques sur la scrofule, considérée en ellemême et dans ses rapports avec la syphilis, la dartre et l’arthritis. 2nd edition, Paris, 1861. Page 145 and 501.
- ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. p. 1265. ISBN 0-7216-0187-1.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Historical Perspective
Overview
Bazin disease is named for Pierre-Antoine-Ernest Bazin.[1][2]
References
- ↑ Template:WhoNamedIt
- ↑ P. A. E. Bazin. Leçons théoriques et cliniques sur la scrofule, considérée en ellemême et dans ses rapports avec la syphilis, la dartre et l’arthritis. 2nd edition, Paris, 1861. Page 145 and 501.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
Overview
Bazin disease is a type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis.
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Causes
Overview
Bazin disease was formerly thought to be a reaction to tuberculum bacillus, but it is now considered a panniculitis that is not associated with a single defined pathogen. [1]
References
- ↑ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease (7th ed.). St. Louis, Mo: Elsevier Saunders. p. 1265. ISBN 0-7216-0187-1.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Differentiating Bazin disease from other Diseases
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References
Epidemiology and Demographics
Overview
Bazin disease is seen most commonly in adolescent and menopausal women.
Epidemiology and Demographics
Age
- It most commonly affects women aged 20-30 years.
Gender
- It occurs mainly in women.
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Risk Factors
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Overview
Bazin disease is initiated or exacerbated by cold weather.
References
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Natural History, Complications and Prognosis
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References
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | Other Diagnostic Studies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]