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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Burkitt's lymphoma natural history, complications and prognosis

Introduction

Overview

Overview

The prognosis varies with the age, children have the most favorable prognosis. Burkitt’s lymphoma in children is associated with a 5 year survival rate of 90%. The presence of metastasis in bone marrow or CNS is associated with a particularly poor prognosis among patients with Burkitt’s lymphoma.

Complications

Complications

Common complications of Burkitt’s lymphoma include:

Prognosis

Prognosis

  • In children, prognosis is good with survival rates >90%[5]
  • In adults, prognosis is poor, with a 5-year survival rate of 50% and is even worse with bone marrow or CNS involvement (>30% 5-year survival rate).
References

References

  1. ↑ Comfort AO (2004). “Burkitt’s lymphoma of the jaws: role of dental practitioner in management”. Pac Health Dialog. 11 (1): 89–93. PMID 18181448.
  2. ↑ Aslan G (2013). “Unusual presentation of sporadic Burkitt’s lymphoma originating from the nasal septum: a case report”. J Med Case Rep. 7: 60. doi:10.1186/1752-1947-7-60. PMC 3599746. PMID 23497670.
  3. ↑ Madabhavi I, Patel A, Revannasiddaiah S, Choudhary M, Anand A, Das P; et al. (2014). “Primary esophageal Burkitt’s lymphoma: a rare case report and review of literature”. Gastroenterol Hepatol Bed Bench. 7 (4): 230–7. PMC 4185878. PMID 25289138.
  4. ↑ Wössmann W, Schrappe M, Meyer U, Zimmermann M, Reiter A (2003). “Incidence of tumor lysis syndrome in children with advanced stage Burkitt’s lymphoma/leukemia before and after introduction of prophylactic use of urate oxidase”. Ann Hematol. 82 (3): 160–5. doi:10.1007/s00277-003-0608-2. PMID 12634948.
  5. ↑ Jacobson C, LaCasce A (2014). “How I treat Burkitt lymphoma in adults”. Blood. 124 (19): 2913–20. doi:10.1182/blood-2014-06-538504. PMID 25258344.


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2], Kamal Akbar, M.D.[3]