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Airway obstruction

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Airway obstruction is a respiratory problem caused by increased resistance in the bronchioles (usually from a decreased radius of the bronchioles) that reduces the amount of air inhaled in each breath and the oxygen that reaches the pulmonary arteries. It is different from airway restriction (which prevents air from diffusing into the pulmonary arteries because of some kind of blockage in the lungs).

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Historical Perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

Historical Perspective

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Classification

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Pathophysiology

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Causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hilda Mahmoudi M.D., M.P.H.[2]

Overview

Airway obstruction can be caused by obvious physical obstruction, such as choking or due to a swollen epiglottis in epiglottitis. It can also be caused by less obvious causes of airway compromise such as chronic obstructive pulmonary disease, pneumonia and pulmonary edema. A high index of suspicion needs to be maintained when a person presents with signs of infection and upper airway obstruction, as epiglottitis and peritonsillar abcess can cause rapid cardiorespiratory compromise.

Causes

Common Causes

Causes by Organ System

Cardiovascular Anaphylactic shock , Aortic arch anomalies, Aortic dissection, Hemangioma, Pulmonary edema, Superior vena cava syndrome
Chemical / poisoning Chemical burns,
Dermatologic Hemangioma, Kaposi’s sarcoma
Drug Side Effect ACE inhibitors, Anaphylactic shock , Angioedema, Levodopa, Penicillin, Sedation, Sodium thiopental, Trovafloxacin mesylate
Ear Nose Throat Adenoid hypertrophy, Croup, Dysphagia, Empty nose syndrome, Epiglottitis, Large turbinate, Laryngomalacia, Pallister-Hall syndrome, Peritonsillar abscess, Pharyngeal flap surgery, Pierre Robin syndrome, Retropharyngeal abscess, Rhinoplasty, Subglottic stenosis, Swollen turbinates, Throat cancer, Thyroid cancer, Thyroid Carcinoma, Tonsillectomy, Tracheitis, Tracheomalacia, Tracheotomy, Upper airway obstruction, Uvulopalatopharyngoplasty, Vocal cord problems
Endocrine Thyroid cancer, Thyroid carcinoma
Environmental Foreign body, Hanging
Gastroenterologic Cystic fibrosis, Pallister-Hall syndrome
Genetic Cystic fibrosis, Pallister-Hall syndrome, Pierre Robin syndrome
Hematologic Hemangioma
Iatrogenic Rhinoplasty, Tonsillectomy, Tracheotomy, Uvulopalatopharyngoplasty
Infectious Disease Bacterial infections, Epiglottitis, Infectious mononucleosis, Kaposi’s sarcoma, Peritonsillar abscess, Retropharyngeal abscess, Tracheitis, Viral infections
Musculoskeletal / Ortho Increased neck circumference, Pallister-Hall syndrome, Pierre Robin syndrome
Neurologic Conscious Sedation, Pallister-Hall syndrome, Sedation
Nutritional / Metabolic Obesity, Obesity hypoventilation syndrome
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Opthalmologic No underlying causes
Overdose / Toxicity Sedation
Psychiatric No underlying causes
Pulmonary Aspiration, Asthma, Atelectasis, Bronchiectasis, Bronchiolitis obliterans, Chronic airway obstruction, Chronic obstructive pulmonary disease, Community-acquired pneumonia, Cystic fibrosis, Exercise induced pulmonary hemorrhage, Hospital-acquired pneumonia, Lipid pneumonia, Obesity hypoventilation syndrome, Pneumonia, Pulmonary edema
Renal / Electrolyte Rapidly progressive glomerulonephritis,
Rheum / Immune / Allergy Allergic reactions, Anaphylactic shock , Angioedema, Interleukin 13, Leukotriene,
Sexual No underlying causes
Trauma Aortic dissection, Trauma
Urologic No underlying causes, Pallister-Hall syndrome
Dental No underlying causes
Miscellaneous Smoke burn

Causes in Alphabetical Order

  • Hanging
  • Increased neck circumference
  • Large turbinate
  • Swollen turbinate
  • Throat cancer
  • Vocal cord problems

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Differentiating Airway obstruction from other Diseases

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Epidemiology and Demographics

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Risk Factors

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Screening

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Natural History, Complications and Prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural History

Complications

Inability to relieve the obstruction can cause:

  • Brain damage
  • Breathing failure
  • Death

Prognosis

Prompt treatment is often successful. However, the condition is dangerous and may be fatal, even if treated.

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Diagnosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Other Imaging Findings | Other Diagnostic Studies

Treatment

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case Studies

Case#1

Related Chapters

Stridor

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