Cardiac tumors historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dheeraj Makkar, M.D.[2]

Overview

Realdo Colombo initially reported cardiac tumors in 1559, and Dr. Clarence Crafoord performed the first successful surgical resection of left atrial myxoma in 1954. New chemotherapy drugs and treatment have been developing after the discovery of cardiac tumors.

Historical Perspective

Cardiac Tumors were first described by Realdo Colombo in 1559.^[1]
In 1936, Beck and Maurer were the first to resect right ventricular teratoma. They also resected a left ventricular lipoma in 1951.^[2]
Dr. William Norris was the first to describe a “melanotic heart” with secondary metastases to the heart in 1820.^[3]
In 1952, left atrial myxoma was successfully excised by Bahnson and Newman through a right atriotomy. Unfortunately, the patient succumbed to the procedure after 24 days.^[4]

In 1954, Dr. Clarence Crafoord from Sweden reported the first successful removal of left atrial myxoma in a 40-year-old female presenting with dizziness and transient hemiparesis caused by myxoma.The patient survived for more than 40 years after her surgery.^[1]
Dr. Senning and his team developed perfusion system to ease cardiac surgeries. The Perfusion system comprised of hypothermia, flow, and ventricular fibrillation to prevent embolism.^[1]
In July 1954, they used it for the first time in the excision of left atrial myxoma, performed by Dr. Crafoord. This was a milestone surgery in developing Extracorporeal perfusion system.^[1]

References

Overview