Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Congenital syphilis differential diagnosis
Introduction
Overview
Overview
Congenital syphilis must be differentiated from other TORCH infections.
Differential Diagnosis
Differential Diagnosis
The most important congenital infections, which can be transmitted vertically from mother to fetus are the TORCH infections. These infections have overlapping features and hence, must be differentiated from congenital syphilis :[1][2]
| Congenital Infection | Cardiac Findings | Skin Findings | Ocular Findings | Hepatosplenomegaly | Hydrocephalus | Microcephaly | Intracranial Calcifications | Hearing deficits |
|---|---|---|---|---|---|---|---|---|
| Toxoplasmosis | ✔ | ✔ | ✔ | Diffuse intracranial calcifications | ||||
| Congenital Syphils | ✔ | |||||||
| Rubella | ✔ | ✔ | ✔ | ✔ | ||||
| Cytomegalovirus (CMV) | ✔ | ✔ | ✔ | Periventricular calcifications | ✔ | |||
| Herpes simplex virus (HSV) | ✔ | ✔ | ✔ | ✔ | ||||
| Parvovirus B19 | ✔ |
References
References
- ↑ Neu N, Duchon J, Zachariah P (2015). “TORCH infections”. Clin Perinatol. 42 (1): 77–103, viii. doi:10.1016/j.clp.2014.11.001. PMID 25677998.
- ↑ Ajij M, Nangia S, Dubey BS (2014). “Congenital rubella syndrome with blueberry muffin lesions and extensive metaphysitis”. J Clin Diagn Res. 8 (12): PD03–4. doi:10.7860/JCDR/2014/10271.5293. PMC 4316306. PMID 25654000.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]