
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Cystoviridae
Introduction
Characteristics
Characteristics
All cystoviruses are distinguished by their three strands (analogous to chromosomes) of dsRNA, totalling ~14 kb in length and their protein and lipid outer layer. No other bacteriophage have any lipid in their outer coat, though the Tectiviridae and the Corticoviridae have lipids within their capsids.
Most identified cystoviruses infect Pseudomonas species, but this is likely biased due to the method of screening and enrichment [1]. The type species is Pseudomonas phage Φ6, but there are many other members of this family. Φ7, Φ8, Φ9, Φ10, Φ11, Φ12 and Φ13 have been identified and named [2], but other cystoviruses have also been isolated [1].
Members of the Cystoviridae appear to be most closely related to the Reoviridae [3], but also share homology with the Totiviridae. Cystoviruses are the only bacteriophage that are more closely related to viruses of eukaryotes than to other phage.
References
References
- ↑ 1.0 1.1 Silander, O. K., D. M. Weinreich, K. M. Wright, K. J. O’Keefe, C. U. Rang, P. E. Turner, and L. C. 2005. Widespread genetic exchange among terrestrial bacteriophages. Proc. Natl. Acad. Sci. USA 102:19009-19014. full text
- ↑ Mindich, L., X. Qiao, J. Qiao, S. Onodera, M. Romantschuk, and D. Hoogstraten. 1999. Isolation of additional bacteriophages with genomes of segmented double-stranded RNA. J. Bacteriol. 181:4505-4508. full text
- ↑ Butcher, S. J., T. Dokland, P. M. Ojala, D. H. Bamford, and S. D. Fuller. 1997. Intermediates in the assembly pathway of the double-stranded RNA virus phi6. EMBO J. 16:4477-4487. full text
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
