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Reliable, easy-to-read patient information on common medical conditions β€” written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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De Quervain's thyroiditis medical therapy

Introduction

Overview

Overview

The mainstay of therapy for de Quervain’s thyroiditis is aspirin or non-steroidal anti-inflammatory drugs for pain control. Beta-adrenergic blockers are recommended for the patients who develop thyrotoxic symptoms. Corticosteroids are usually used in severely ill patients. Levothyroxine is required if the patient develops hypothyroidism following the resolution of the hyperthyroid state.

Medical Therapy

Medical Therapy

De Quervain’s thyroiditis

The drugs used in the treatment of de Quervain’s thyroiditis are:[1][2][3][4]

  • For pain
    • Preferred regimen (1): Naproxen: 500 to 1000 mg per day in two divided doses
    • Preferred regimen (2): Ibuprofen: 1200 to 3200 mg per day in three or four divided doses
  • For severe condition
    • Preferred regimen (1): Prednisone: 40 mg per day orally
  • For hypothyroidism
  • Preferred regimen (1): Synthetic levothyroxine (L-T4): 1.6–1.8 ΞΌg/kg per day orally
  • For thyrotoxic symptoms
    • Preferred regimen (1): atenolol: 25-200mg per day orally
    • Preferred regimen (2): metoprolol: 25-200mg per day orally
References

References

  1. ↑ Engkakul P, Mahachoklertwattana P, Poomthavorn P (2011). “EponymΒ : de Quervain thyroiditis”. Eur. J. Pediatr. 170 (4): 427–31. doi:10.1007/s00431-010-1306-4. PMIDΒ 20886353.
  2. ↑ Yamamoto M, Saito S, Sakurada T, Fukazawa H, Yoshida K, Kaise K, Kaise N, Nomura T, Itagaki Y, Yonemitsu K (1987). “Effect of prednisolone and salicylate on serum thyroglobulin level in patients with subacute thyroiditis”. Clin. Endocrinol. (Oxf). 27 (3): 339–44. PMIDΒ 3427792.
  3. ↑ VolpΓ© R (1993). “The management of subacute (DeQuervain’s) thyroiditis”. Thyroid. 3 (3): 253–5. PMIDΒ 8257868.
  4. ↑ Feely J, Peden N (1984). “Use of beta-adrenoceptor blocking drugs in hyperthyroidism”. Drugs. 27 (5): 425–46. PMIDΒ 6144501.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]