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Echinococcosis laboratory findings

Introduction

Overview

Overview

In the patients suspected of echinococcosis, enzyme-linked immunosorbent assay (ELISA) and the indirect hemagglutination test are highly sensitive procedures for the initial screening of serum for cystic echinococcosis. In case of alveolar echinococcosis, serologic test results are usually positive at high titers. Comparing a patient’s titers with both purified-specific and shared antigens permits the serologic discrimination between patients infected with E. multilocularis and those infected with E. granulosus.

Laboratory Findings

Laboratory Findings

In the patients suspected of echinococcosis, enzyme-linked immunosorbent assay (ELISA) and the indirect hemagglutination test are highly sensitive procedures for the initial screening. [1]

Serologic Tests

Enzyme-linked immunosorbent assay (ELISA) and the indirect hemagglutination test are highly sensitive procedures for the initial screening of serum. Specific confirmation of reactivity can be obtained by demonstrating echinococcal antigens by immunodiffusion (arc 5) procedures or immunoblot assays (8-, 21– kD bands).

Serologic test results are usually positive at high titers. Comparing a patient’s titers with both purified-specific and shared antigens permits the serologic discrimination between patients infected with E. multilocularis and those infected with E. granulosus.

Laboratory Tets Findings
CBC
Antibody testing

(Immunoglobulin concentrations)

Liver function tests
Serology tests
References

References

  1. ↑ Siracusano A, Teggi A, Ortona E (2009). “Human cystic echinococcosis: old problems and new perspectives”. Interdiscip Perspect Infect Dis. 2009: 474368. doi:10.1155/2009/474368. PMC 2771156. PMID 19888428.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Mahshid Mir, M.D. [2] ; Cafer Zorkun, M.D., Ph.D. [3]; Kalsang Dolma, M.B.B.S.[4]; Aditya Ganti M.B.B.S. [5]