Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Eosinophilic pneumonia causes
Introduction
Overview
Overview
Causes of eosinophilic lung diseases are acute eosinophilic pneumonia, chrnoic eosinophilic pneumonia, tropical pulmonary eosinophilia, eosinophilic granulomatosis with polyangitis, allergic bronchopulmonary aspergillosis, and medications such as nonsteroidal anti-inflammatory drugs, Anticonvulsants, Antidepressants, Angiotensin converting enzyme inhibitors, and Beta blockers.
Causes
Causes
Acute eosinophilic pneumonia (AEP)
- The cause of acute eosinophilic pneumonia is unknown but an acute hypersensitivity reaction is suggested.[1]
Chrnoic eosinophilic pneumonia (CEP)
- Chronic eosinophilic pneumonia is an characterized by an abnormal and marked accumulation of eosinophils in the interstitium and alveolar spaces of the lung.[2]
Transpulmonary passage of helminth larvae (Löffler syndrome)
- Three types of helminths, Ascaris, hookworms, and Strongyloides stercoralis, have larvae that reach the lungs, penetrate into alveoli, and ascend the airways then reach the gastrointestinal tract.
- Ascaris is the most common cause of Löffler syndrome worldwide.[3][4]
Tropical pulmonary eosinophilia
- Tropical pulmonary eosinophilia is immune response to the lymphatic filariae and Wuchereria bancrofti.[5]
- Pulmonary function tests may show a mixed restrictive and obstructive abnormality with a reduction in diffusion capacity.[6]
Eosinophilic granulomatosis with polyangitis
- Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) is a vasculitic disorder often characterized by sinusitis, asthma, and prominent peripheral blood eosinophilia.[7]
- It is the sole form of vasculitis that is associated with both eosinophilia and frequent lung involvement.
- In addition to the lungs, the skin and the cardiovascular, gastrointestinal, renal, and neurologic systems may also be involved.
Allergic bronchopulmonary aspergillosis
- Allergic bronchopulmonary aspergillosis is a complex hypersensitivity reaction that occurs when airways become colonized by Aspergillus.[8]
- Immunologic responses elicited by Aspergillus fumigatus are responsible for this syndrome. It can lead to bronchiectasis, and fibrosis.
Drugs and toxins
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a drug-induced hypersensitivity reaction that includes skin eruption, eosinophilia, atypical lymphocytosis, lymphadenopathy, and kidney involvement. Drugs causing DRESS are:[9]
References
References
- ↑ Cottin V (2016). “Eosinophilic Lung Diseases”. Clin Chest Med. 37 (3): 535–56. doi:10.1016/j.ccm.2016.04.015. PMID 27514599.
- ↑ Yıldız T, Dülger S (2018). “Non-astmatic Eosinophilic Bronchitis”. Turk Thorac J. 19 (1): 41–45. doi:10.5152/TurkThoracJ.2017.17017. PMC 5783052. PMID 29404185.
- ↑ . PMID 13331628. Missing or empty
|title=(help) - ↑ Yang Z, Lei W, Xiao-Li L, Xiao-Jun T, Wei L, Yi-Jun A; et al. (2017). “[Clinical features of imported schistosomiasis mansoni in Beijing City：a report of 6 cases]”. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 29 (2): 150–154. doi:10.16250/j.32.1374.2016207. PMID 29469316.
- ↑ . PMID 15486834. Missing or empty
|title=(help) - ↑ Jai B. Mullerpattan, Zarir F. Udwadia & Farokh E. Udwadia (2013). “Tropical pulmonary eosinophilia–a review”. The Indian journal of medical research. 138 (3): 295–302. PMID 24135173. Unknown parameter
|month=ignored (help) - ↑ L. Guillevin, P. Cohen, M. Gayraud, F. Lhote, B. Jarrousse & P. Casassus (1999). “Churg-Strauss syndrome. Clinical study and long-term follow-up of 96 patients”. Medicine. 78 (1): 26–37. PMID 9990352. Unknown parameter
|month=ignored (help) - ↑ . PMID 16612769. Missing or empty
|title=(help) - ↑ Peter W. Kim, Alfred F. Sorbello, Ronald T. Wassel, Tracy M. Pham, Joseph M. Tonning & Sumathi Nambiar (2012). “Eosinophilic pneumonia in patients treated with daptomycin: review of the literature and US FDA adverse event reporting system reports”. Drug safety. 35 (6): 447–457. doi:10.2165/11597460-000000000-00000. PMID 22612850. Unknown parameter
|month=ignored (help) - ↑ Reyes F, Vaitkus V, Al-Ajam M (2018). “A case of cocaine-induced eosinophilic pneumonia: Case report and review of the literature”. Respir Med Case Rep. 23: 98–102. doi:10.1016/j.rmcr.2017.12.012. PMC 5805849. PMID 29487790.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]