Erdheim-Chester disease
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Erdheim-Chester syndrome; polyostotic sclerosing histiocytosis; ECD
Overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Erdheim-Chester disease is a rare form of non-Langerhans-cell histiocytosis. Usually, onset is in middle age. The disease involves an infiltration of lipid-laden macrophages, multinucleated giant cells, an inflammatory infiltrate of lymphocytes and histiocytes in the bone marrow, and a generalized sclerosis of the long bones.[1]
References
- ↑ “Erdheim-Chester disease at the Disease Database”. Retrieved 2007-03-25.
Historical Perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
The first case of ECD was reported by W. Chester and Jakob Erdheim in 1930.[1]
References
Pathophysiology
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References
Causes
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References
Differentiating Erdheim-Chester disease from other Diseases
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References
Epidemiology and Demographics
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Epidemiology and Demographics
Age
ECD affects predominantly adults, with a mean age of 53 years.[1]
References
Natural History, Complications and Prognosis
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References
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Case Studies
Case Studies
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