
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Esophageal stricture causes
Introduction
Overview
Overview
Common causes of esophageal stricture include gastroesophageal reflux disease and caustic ingestions.
Causes
Causes
Life-threatening Causes
- Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of esophageal stricture, however complications resulting from untreated esophageal stricture is common.
Common Causes
Esophageal stricture may be caused by:[1]
- Gastroesophageal reflux disease[2]
- Caustic ingestions[3]
- Radiation therapy for thoracic or head and neck tumors[4]
- Esophageal cancer
- Congenital causes such as rings and webs[5]
- Nasogastric intubation[6]
Less Common Causes
Less common causes of esophageal stricture include:
- Dyskeratosis congenita (DC)[9]
- Rare dermatologic diseases (eg, epidermolysis bullosa dystrophica)[10]
- Mediastinal fibrosis due to tuberculosis or idiopathic fibrosing mediastinitis[11]
- Drug-induced stricture:[12]
- Aspirin and anti-inflammatory medications[13]
- Tetracycline
- Doxycycline
- Clindamycin
- Bisphosphonates
- Potassium chloride
- Quinidine preparations
- Iron compounds
- Emepronium
- Alprenolol
- PinaveriumÂ
- Tracheoesophageal fistula repair and esophageal stricture at the anastomosis[15]
- Esophageal diverticula[16]
- Increased level of gastric acid exposure to esophageal tissue, for example:
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | Caustic ingestion |
| Dental | No underlying causes |
| Dermatologic | Dyskeratosis congenita (DC), epidermolysis bullosa dystrophica |
| Drug Side Effect | Drug-induced stricture:[12]
|
| Ear Nose Throat | No underlying causes |
| Endocrine | Zollinger-Ellison syndrome, |
| Environmental | No underlying causes |
| Gastroenterologic | Gastroesophageal reflux disease, Eosinophilic esophagitis, Esophageal diverticula, Zollinger-Ellison syndrome, Systemic sclerosis |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | Previous surgery on the esophagus, Radiation therapy for thoracic or head and neck tumors, Esophageal sclerotherapy,Tracheoesophageal fistula repair, Nasogastric tube placement, Heller myotomy for achalasia |
| Infectious Disease | Infectious esophagitis
|
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | Mediastinal fibrosis due to tuberculosis or idiopathic fibrosing mediastinitis |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | Systemic sclerosis |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
List the causes of the disease in alphabetical order.
- Caustic ingestions
- Drug-induced stricture
- Dyskeratosis congenita (DC)
- Eosinophilic esophagitis
- Esophageal diverticula
- Esophageal sclerotherapy
- Gastroesophageal reflux disease
- Increased level of gastric acid exposure to esophageal tissue
- Infectious esophagitis
- Mediastinal fibrosis due to tuberculosis or idiopathic fibrosing mediastinitis
- Nasogastric intubation
- Radiation therapy for thoracic or head and neck tumors
- Rare dermatologic diseases (eg, epidermolysis bullosa dystrophica)
- Tracheoesophageal fistula repair and esophageal stricture at the anastomosis
References
References
- ↑ Csendes A, Braghetto I (1992). “Surgical management of esophageal strictures”. Hepatogastroenterology. 39 (6): 502–10. PMID 1483661.
- ↑ Marks RD, Richter JE (1993). “Peptic strictures of the esophagus”. Am. J. Gastroenterol. 88 (8): 1160–73. PMID 8338082.
- ↑ Wasserman RL, Ginsburg CM (1985). “Caustic substance injuries”. J. Pediatr. 107 (2): 169–74. PMID 4020540.
- ↑ Coia LR, Myerson RJ, Tepper JE (1995). “Late effects of radiation therapy on the gastrointestinal tract”. Int. J. Radiat. Oncol. Biol. Phys. 31 (5): 1213–36. doi:10.1016/0360-3016(94)00419-L. PMID 7713784.
- ↑ Khanna N (2006). “How do I dilate a benign esophageal stricture?”. Can J Gastroenterol. 20 (3): 153–5. PMC 2582967. PMID 16550258.
- ↑ Luedtke P, Levine MS, Rubesin SE, Weinstein DS, Laufer I (2003). “Radiologic diagnosis of benign esophageal strictures: a pattern approach”. Radiographics. 23 (4): 897–909. doi:10.1148/rg.234025717. PMID 12853664.
- ↑ Guynn TP, Eckhauser FE, Knol JA, Raper SE, Mulholland MW, Nostrant TT, Elta GH, Barnett JL (1991). “Injection sclerotherapy-induced esophageal strictures. Risk factors and prognosis”. Am Surg. 57 (9): 567–71, discussion 571–2. PMID 1928999.
- ↑ Furuta, Glenn T.; Ingelfinger, Julie R.; Katzka, David A. (2015). “Eosinophilic Esophagitis”. New England Journal of Medicine. 373 (17): 1640–1648. doi:10.1056/NEJMra1502863. ISSN 0028-4793.
- ↑ Jonassaint NL, Guo N, Califano JA, Montgomery EA, Armanios M (2013). “The gastrointestinal manifestations of telomere-mediated disease”. Aging Cell. 12 (2): 319–23. doi:10.1111/acel.12041. PMC 3602337. PMID 23279657.
- ↑ Guerra-Leal JD, Meester I, Cantu-Gonzalez JR, Ornelas-Cortinas G, Montemayor-Martinez A, Salas-Alanis JC (2016). “The Importance of Esophagography in Patients With Recessive Dystrophic Epidermolysis Bullosa”. AJR Am J Roentgenol: 1–4. doi:10.2214/AJR.16.16115. PMID 27384758.
- ↑ Goenka MK, Gupta NM, Kochhar R, Rungta U, Vaiphei K, Nagi B, Suri S (1995). “Mediastinal fibrosis: an unusual cause of esophageal stricture”. J. Clin. Gastroenterol. 20 (4): 331–3. PMID 7665827.
- ↑ 12.0 12.1 Bonavina L, DeMeester TR, McChesney L, Schwizer W, Albertucci M, Bailey RT (1987). “Drug-induced esophageal strictures”. Ann Surg. 206 (2): 173–83. PMC 1493104. PMID 3606243.
- ↑ 13.0 13.1 Kikendall JW, Friedman AC, Oyewole MA, Fleischer D, Johnson LF (1983). “Pill-induced esophageal injury. Case reports and review of the medical literature”. Dig. Dis. Sci. 28 (2): 174–82. PMID 6825537.
- ↑ Wilcox CM (2013). “Overview of infectious esophagitis”. Gastroenterol Hepatol (N Y). 9 (8): 517–9. PMC 3980995. PMID 24719600.
- ↑ Lakoma A, Fallon SC, Mathur S, Kim ES (2013). “Use of Mitomycin C for Refractory Esophageal Stricture following Tracheoesophageal Fistula Repair”. European J Pediatr Surg Rep. 1 (1): 24–6. doi:10.1055/s-0033-1341418. PMC 4335951. PMID 25755944.
- ↑ Smith, C. Daniel (2015). “Esophageal Strictures and Diverticula”. Surgical Clinics of North America. 95 (3): 669–681. doi:10.1016/j.suc.2015.02.017. ISSN 0039-6109.
- ↑ Ebert, Ellen C. (2008). “Esophageal disease in progressive systemic sclerosis”. Current Treatment Options in Gastroenterology. 11 (1): 64–69. doi:10.1007/s11938-008-0008-8. ISSN 1092-8472.
- ↑ 18.0 18.1 Luedtke, Pia; Levine, Marc S.; Rubesin, Stephen E.; Weinstein, Donald S.; Laufer, Igor (2003). “Radiologic Diagnosis of Benign Esophageal Strictures: A Pattern Approach”. RadioGraphics. 23 (4): 897–909. doi:10.1148/rg.234025717. ISSN 0271-5333.
- ↑ Ferguson MK (1991). “Achalasia: current evaluation and therapy”. Ann. Thorac. Surg. 52 (2): 336–42. PMID 1863166.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
