Familial amyloidosis echocardiography and ultrasound

Echocardiography may be helpful in the diagnosis of familial amyloidosis. Findings on an echocardiography suggestive of familial amyloidosis include sparkling or speckled appearance of the left ventricular thickening, hypertrophied right ventricle, diastolic dysfunction with restrictive filling pattern (in the advanced stages), severe atrial dilatation, thickening of the interatrial septum, pericardial effusion, and prominent valves.

• Findings on echocardiography suggestive of amyloidosis include:^[1][2][3]
  • Sparkling or speckled appearance of the left ventricular thickening
  • Hypertrophied right ventricle
  • Diastolic dysfunction with restrictive filling pattern (in the advanced stages)
  • Severe atrial dilatation
  • Thickening of the interatrial septum
  • Pericardial effusion
  • Prominent valves

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