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Fournier gangrene laboratory tests

Steven C. Campbell, M.D., Ph.D.; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[1]; Jesus Rosario Hernandez, M.D. [2]

Overview

Overview

The most important laboratory findings in necrotizing fasciitis include C-reactive protein, total white blood cell count, Hemoglobin, Sodium, Creatinine, Glucose. The main importance of these laboratory findings are due to their usage as a distinguishing method for differentiating necrotizing fasciitis from other soft tissue infections.

Laboratory Findings

Laboratory Findings

The most important laboratory findings in necrotizing fasciitis include C-reactive protein, total white blood cell count, Hemoglobin, Sodium, Creatinine, Glucose. The main importance of these laboratory findings are due to their usage as a distinguishing method for differentiating necrotizing fasciitis from other soft tissue infections. Laboratory findings consistent with the diagnosis of Fournier gangrene include:

Laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring system

LRINEC is a diagnostic scoring system used to distinguish necrotizing fasciitis from other soft tissue infections.[1][2] It was first established by Wong et al in 2004.

Variable Score
0 +1 +2 +3 +4
C-reactive protein (mg/dL) <150 >150
Total White Blood Cell Count (/mm3) <15 15-25 >25
Hemoglobin (g/dL) <13.5 11-13.5 <11
Sodium (mmol/L) ≥135 <135
Creatinine (μmol/L) <141 >141
Glucose (mmol/L) <10 >10
  • Score of ≤5 indicates low risk
  • Score of 6-7 indicates intermediate risk
  • Score of ≥8 indicates high risk
References

References

  1. Wong CH, Khin LW, Heng KS, Tan KC, Low CO (2004). “The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections”. Crit Care Med. 32 (7): 1535–41. PMID 15241098.
  2. Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS (2012). “Fournier’s Gangrene: Current Practices”. ISRN Surg. 2012: 942437. doi:10.5402/2012/942437. PMC 3518952. PMID 23251819.

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