
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Gallbladder volvulus pathophysiology
Introduction
Overview
Overview
Torsion of gall bladder leads to occlusion of the cystic duct and the cystic artery. This torsion can be complete (180o – 360o) or incomplete (< 180o). Incomplete torsion causes obstruction of the bile duct and vascular supply may be spared. In complete obstruction both are compromised. This occlusion leads to an increased amount of bile in the lumen and a decreased flow of blood to the organ. Increased pressure in the lumen with ischemia leads to acute inflammation causing a surgical emergency.
Pathophysiology
Pathophysiology
Gross Pathology
- Enlarged and distended gallbladder.
- Torsion along the long axis of the peduncle.
- Thick edematous wall with mucosal congestion.
Microscopic Pathology
- Extensive necrosis of the wall.[1]
- Findings may be similar to gangrenous cholecystitis due to severe ischemia.
- The GB wall shows almost complete coagulation necrosis with intramural hemorrhages.
- A thin layer of degenerated collagen ο¬ber, derived from the mucosa and proper muscle, may be seen along the inner side, and a thin subserosal connective tissue layer may seen along the outermost side.
References
References
- β Aibe H, Honda H, Kuroiwa T, Yoshimitsu K, Irie H, Shinozaki K; et al. (2002). “Gallbladder torsion: case report”. Abdom Imaging. 27 (1): 51β3. PMIDΒ 11740608.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
