
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Gonadoblastoma natural history, complications and prognosis
Introduction
Overview
Overview
Gonadoblastoma per se is a benign tumor, however, it has the capacity to convert to dysgerminoma or other more malignant germ cell tumors and produce steroids with resultant virilization. Prognosis is generally excellent after removing the tumor.
Natural History, Complications, and Prognosis
Natural History, Complications, and Prognosis
Natural History
- Gonadoblastoma usually develops in the first and second decades of life.[1]
- If complicated by an invasive germ cell tumor, then prognosis depends on the staging of the tumor.[2]
- It is usually diagnosed during a workup for sex organ developmental disorders, primary amenorrhea, and/or virilization.
Complications
- Common complications of gonadoblastoma include:[1]
- Dysgerminoma
- Seminoma
- Other gonadal malignancies
Prognosis
References
References
- ↑ 1.0 1.1 Sperling, M (2014). Pediatric endocrinology. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-4858-7.
- ↑ Saia, Philip (2018). Clinical gynecologic oncology. Philadelphia, PA: Elsevier. ISBN 978-0-323-40067-1.
- _ScienceDirect_3-0|↑ “Pediatric Endocrinology | ScienceDirect”.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
