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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Hemophilia risk factors

Introduction

Overview

Overview

The most potent risk factor in the development of hemophilia is the family history of hemophilia. Other risk factors include male sex and malignancies.

Risk Factors

Risk Factors

Common Risk Factors[1][2][3][4]

Risk Factors for Acquired Hemophilia[5][6][7][8]

References

References

  1. ↑ Mannucci PM, Tuddenham EG (June 2001). “The hemophilias–from royal genes to gene therapy”. N. Engl. J. Med. 344 (23): 1773–9. doi:10.1056/NEJM200106073442307. PMID 11396445.
  2. ↑ Ingram, G I (1976). “The history of haemophilia”. Journal of Clinical Pathology. 29 (6): 469–479. doi:10.1136/jcp.29.6.469. ISSN 0021-9746.
  3. ↑ How Hemophilia is Inherited | Hemophilia | NCBDDD | CDC. Available at http://www.cdc.gov/ncbddd/hemophilia/inheritance-pattern.html. Accessed on Sept 20, 2016
  4. ↑ Di Michele DM, Gibb C, Lefkowitz JM, Ni Q, Gerber LM, Ganguly A (March 2014). “Severe and moderate haemophilia A and B in US females”. Haemophilia. 20 (2): e136–43. doi:10.1111/hae.12364. PMID 24533955.
  5. ↑ Napolitano M, Siragusa S, Mancuso S, Kessler CM (January 2018). “Acquired haemophilia in cancer: A systematic and critical literature review”. Haemophilia. 24 (1): 43–56. doi:10.1111/hae.13355. PMID 28960809.
  6. ↑ Knoebl P, Marco P, Baudo F, Collins P, Huth-Kühne A, Nemes L; et al. (2012). “Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2)”. J Thromb Haemost. 10 (4): 622–31. doi:10.1111/j.1538-7836.2012.04654.x. PMID 22321904.
  7. ↑ Kruse-Jarres R, Kempton CL, Baudo F, Collins PW, Knoebl P, Leissinger CA; et al. (2017). “Acquired hemophilia A: Updated review of evidence and treatment guidance”. Am J Hematol. 92 (7): 695–705. doi:10.1002/ajh.24777. PMID 28470674.
  8. ↑ Collins P, Baudo F, Huth-Kühne A, Ingerslev J, Kessler CM, Castellano ME et al. (2010) Consensus recommendations for the diagnosis and treatment of acquired hemophilia A. BMC Res Notes 3 ():161. DOI:10.1186/1756-0500-3-161 PMID: 20529258

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]Simrat Sarai, M.D. [3]Fahd Yunus, M.D. [4]Vahid Eidkhani, M.D.