Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Hemosiderosis classification
Introduction
Overview
Overview
Based on the duration of symptoms, pulmonary hemosiderosis may be classified as either acute or chronic phase.Pulmonary hemosiderosis may be classified into three groups based on disease characteristic: first group with circulating anti-glomerular basement membrane (anti-GBM) antibodies, second group, with immune complex disease, and the third group without known immunologic association or (IPH).
Classification
Classification
Based on the duration of symptoms, pulmonary hemosiderosis may be classified as either acute or the chronic phase.
- In the acute phase, patients present with sudden onset of severe dyspnea and hemoptysis, which, if not treated immediately, could be fatal.
- In the chronic phase, some children may present with weight loss, and failure to thrive or hypoxemic respiratory failure.
IPH may be classified into three groups based on disease characteristic:[1]
- Group 1 pulmonary hemosiderosis involves PH with circulating anti-GMB antibodies which affecting the capillary system.
- Group 2 pulmonary hemosiderosis involves PH with an immune complex disease such as systemic lupus erythematosus (SLE).
- Group 3 pulmonary hemosiderosis involves no demonstrable immune system involvement.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]