
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Hepatitis E physical examination
Introduction
Overview
Overview
Patients with hepatitis E typically have a normal physical exam. Symptomatic patients may present with: fever, jaundice, hepatomegaly and splenomegaly, and in more advanced stages of the disease neurological manifestations, such as confusion and motor deficits.[1][2][3]
Physical Examination
Physical Examination
Vitals
Temperature
- A fever may be present
Pulse
Rate
- Tachycardia may be present
Respiratory Rate
- Tachypnea may be present
Skin
- Jaundice may be present
- Palmar erythema may be present
- Spider angiomata may be present
Eyes
- Icteric sclera may be present
Abdomen
- Abdominal distention may be present
- Abdominal tenderness may be present, particularly on the right upper quadrant
- Hepatomegaly may be present
- Splenomegaly may be present
Neurologic
- Asterixis may be present
- Neurologic manifestations, in cases of HEV progression to hepatic encephalopathy, include a wide spectrum of cognitive impairment and motor system abnormalities.[4]
Extrahepatic Manifestations
- Arthralgia
- Palpable purpura
References
References
- β Kamar N, Bendall R, Legrand-Abravanel F, Xia NS, Ijaz S, Izopet J; et al. (2012). “Hepatitis E.” Lancet. 379 (9835): 2477β88. doi:10.1016/S0140-6736(11)61849-7. PMIDΒ 22549046.
- β Wedemeyer H, Pischke S, Manns MP (2012). “Pathogenesis and treatment of hepatitis e virus infection”. Gastroenterology. 142 (6): 1388β1397.e1. doi:10.1053/j.gastro.2012.02.014. PMIDΒ 22537448.
- β Aggarwal R, Jameel S (2011). “Hepatitis E.” Hepatology. 54 (6): 2218β26. doi:10.1002/hep.24674. PMIDΒ 21932388.
- β Vilstrup H, Amodio P, Bajaj J, Cordoba J, Ferenci P, Mullen KD; et al. (2014). “Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study Of Liver Diseases and the European Association for the Study of the Liver”. Hepatology. 60 (2): 715β35. doi:10.1002/hep.27210. PMIDΒ 25042402.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: JoΓ£o AndrΓ© Alves Silva, M.D. [2]
