Hepatoblastoma risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

Risk Factors

The table below lists risk factors for hepatoblastoma:^[1]


Associated Disorder	Clinical findings

Aicardi syndrome	Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies
Beckwith-Wiedemann syndrome	Hemihypertrophy, hemihyperplasia
Familial adenomatous polyposis	Adenoma, hepatoblastoma
Glycogen storage diseases I–IV	Symptoms vary by individual disorder
Low birth weight infants	Preterm and small-for-gestation-age neonates
Simpson-Golabi-Behmel syndrome	Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of Wilms tumor
Trisomy 18, other trisomies	Trisomy 18: Microcephaly and micrognathia, clenched fists with overlapping fingers, and failure to thrive

References

↑ ^1.0 ^1.1 Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015

Overview