Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Hereditary spherocytosis physical examination
Introduction
Overview
Overview
The physical examination findings in hereditary spherocytosis include; scleral icterus, jaundice, splenomegaly. Right upper quadrant abdominal pain may be elicited if gallbladder disease is present.
Physical Examination
Physical Examination
- The physical examination findings in hereditary spherocytosis include:[1]
- Palpable spleens have been detected in more than 75% of affected subjects. The liver is normal in size and function.
- Another important clue is right upper quadrant abdominal pain indicative of gallbladder disease. This is especially important if the patient has a family history of gallbladder disease.
- Any patient who presents with profound and sudden anemia and reticulocytopenia with the aforementioned physical findings also should have hereditary spherocytosis in the differential diagnosis.[2]
References
References
- ↑ Perrotta, Silverio; Gallagher, Patrick G; Mohandas, Narla (2008). “Hereditary spherocytosis”. The Lancet. 372 (9647): 1411–1426. doi:10.1016/S0140-6736(08)61588-3. ISSN 0140-6736.
- ↑ Bolton-Maggs PH, Stevens RF, Dodd NJ, Lamont G, Tittensor P, King MJ; et al. (2004). “Guidelines for the diagnosis and management of hereditary spherocytosis”. Br J Haematol. 126 (4): 455–74. doi:10.1111/j.1365-2141.2004.05052.x. PMID 15287938.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: