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Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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High anion gap metabolic acidosis critical pathways

Introduction

Approach

Approach

metabolic acidosis critical pathways
Anion gap High Normal Low
Delta-delta (ΔΔ) value Greater than 2 Between 1 and 2 Less than 1
Definition

Definition

  • Delta-Delta value is used to determine whether there is an additional metabolic acid-base disturbance or not.
  • Delta-Delta (ΔΔ) = Delta anion gap (ΔAG) / Delta bicarbonate (ΔHCO3)
    • Delta anion gap (ΔAG) = Calculated anion gap – Expected anion gap
      • Calculated anion gap = [Na+] – [Cl–] – [HCO3–]
      • Expected anion gap = 2.5 x serum albumin level
    • Delta bicarbonate (ΔHCO3) = 24 – serum bicarbonate level
References

References

Template:WikiDoc Sources

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]