Health Dictionary
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Histiocytosis classification
Introduction
Overview
Overview
Classification
Classification
There are competing systems for classifying histiocytoses. According to the 1999 classification proposed by the World Health Organization, they can be divided into three categories.[1]. However, the classifications in ICD10 and MeSH are slightly different, as shown below:
| Name | WHO | ICD10 | MeSH |
| Langerhans cell histiocytosis (LCH) | I | D76.0 | Langerhans-cell histiocytosis |
| Juvenile xanthogranuloma (JXG) | II | D76.3 | non-Langerhans-cell histiocytosis |
| Hemophagocytic lymphohistiocytosis (HLH) | II | D76.1 | non-Langerhans-cell histiocytosis |
| Niemann-Pick disease | – | E75.2 | non-Langerhans-cell histiocytosis |
| Sea-blue histiocyte syndrome | – | – | non-Langerhans-cell histiocytosis |
| Acute monocytic leukemia | III | C93.0 | malignant histiocytic disorders |
| Malignant histiocytosis | III | C96.1 | malignant histiocytic disorders |
| Erdheim-Chester disease | – | C96.1 | malignant histiocytic disorders |
Types of LCH have also been known as “Eosinophilic Granuloma“, “Hand-Schuller-Christian Disease“, “Letterer-Siwe Disease“, and “Histiocytosis X“. (See LCH history for details).
References
References
- ↑ Harris N, Jaffe E, Diebold J, Flandrin G, Muller-Hermelink H, Vardiman J, Lister T, Bloomfield C (1999). “The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. Report of the Clinical Advisory Committee meeting, Airlie House, Virginia, November, 1997”. Ann Oncol. 10 (12): 1419–32. PMID 10643532.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]