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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Hypocalcemia history and symptoms

Introduction

Overview

Overview

Clinical presentation of hypocalcemia reflects the serum level of ionized calcium and depends on the severity of any concurrent electrolyte imbalance. Overt symptoms occur when ionized calcium falls below 3.2 mg/dL (0.8 mmol/L). An abrupt fall in the serum calcium level typically manifests as neuromuscular hyperexcitability in the form of tetany and tingling. Patients who develop hypocalcemia gradually may be asymptomatic. In addition to fatigue and muscle weakness, longstanding hypocalcemia is usually associated with neuropsychiatric symptoms.

History and Symptoms

History and Symptoms

The majority of patients with mild hypocalcemia are asymptomatic

Common Symptoms

Common symptoms of hypocalcemia include:[1][2][3][4]

Neuromuscular symptoms

Central nervous system symptoms

Cardiovascular symptoms

Pulmonary symptoms

Less common symptoms

Less common symptoms of hypocalcemia include[5]

References

References

  1. ↑ Cooper, Mark S.; Gittoes, Neil J. L. (2008-06-07). “Diagnosis and management of hypocalcaemia”. BMJ (Clinical research ed.). 336 (7656): 1298–1302. doi:10.1136/bmj.39582.589433.BE. ISSN 1756-1833. PMC 2413335. PMID 18535072.
  2. ↑ Macefield G, Burke D (February 1991). “Paraesthesiae and tetany induced by voluntary hyperventilation. Increased excitability of human cutaneous and motor axons”. Brain. 114 ( Pt 1B): 527–40. PMID 2004255.
  3. ↑ Carroll R, Matfin G (February 2010). “Endocrine and metabolic emergencies: hypocalcaemia”. Ther Adv Endocrinol Metab. 1 (1): 29–33. doi:10.1177/2042018810366494. PMC 3474611. PMID 23148147.
  4. ↑ Cooper MS, Gittoes NJ (June 2008). “Diagnosis and management of hypocalcaemia”. BMJ. 336 (7656): 1298–302. doi:10.1136/bmj.39582.589433.BE. PMC 2413335. PMID 18535072.
  5. ↑ Carroll R, Matfin G (February 2010). “Endocrine and metabolic emergencies: hypocalcaemia”. Ther Adv Endocrinol Metab. 1 (1): 29–33. doi:10.1177/2042018810366494. PMC 3474611. PMID 23148147.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]