Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Infertility pathophysiology
Introduction
Overview
Overview
Disorders of ovulation make up at least 25% of the cases of infertility worldwide, according to a study done by WHO. Other pathologies such as genital tract infections, pelvic inflammatory disease, endometriosis make up the bulk of female infertility cases.
Pathophysiology
Pathophysiology
Male infertility
- A decrease in sperm count[1]
- Sperm being blocked from being released
- Sperm that do not work properly
- Genetic disease such as Klienefelter syndrome, Noonan syndrome and chromosome Y deletions.
Female infertility
- A fertilized egg or embryo does not survive once it sticks to the lining of the womb (uterus).[2]
- The fertilized egg does not attach to the lining of the uterus
- The eggs cannot move from the ovaries to the womb
- The ovaries have problems producing egg
- Hormonal imbalance such as hyperprolactinemia, hypothyroidism, diabetes mellitus, PCOS which interfere with fertility.
Associated conditions
Associated conditions
References
References
- ↑ Miyamoto T, Minase G, Shin T, Ueda H, Okada H, Sengoku K (2017). “Human male infertility and its genetic causes”. Reprod Med Biol. 16 (2): 81–88. doi:10.1002/rmb2.12017. PMC 5661822. PMID 29259455.
- ↑ “Recent advances in medically assisted conception. Report of a WHO Scientific Group”. World Health Organ Tech Rep Ser. 820: 1–111. 1992. PMID 1642014.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2] Associate Editor(s)-in-Chief: Sanjana Nethagani, M.B.B.S.[3]