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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Kaposi's sarcoma staging

Introduction

Overview

Overview

There is no established system for the staging of Kaposi’s sarcoma among immune competent patients. However, the staging of AIDS-associated Kaposi’s sarcoma is based on the AIDS Clinical Trials Group (ACTG) staging system. According to the ACTG staging system, there are 2 groups of AIDS-associated Kaposi’s sarcoma based on the tumor size, patients immune status, and the presence of any systemic illness.

Staging

Staging

  • There is no established system for the staging of Kaposi’s sarcoma among immune competent patients.
  • The staging of AIDS-associated Kaposi’s sarcoma is based on the AIDS Clinical Trials Group (ACTG) staging system. According to the ACTG staging system, there are 2 groups of AIDS-associated Kaposi’s sarcoma based on the tumor size, patients immune status, and the presence of any systemic illness.[1][2][3][4][5]
Factors Good Risk (Subscript 0) Poor Risk (Subscript 1)

Tumor (T)

Immune system (I)

Systemic illness (S)

  • No previous history of opportunistic infection or thrush
  • B symptoms are not present
  • Karnofsky performance status score ≥ 70
  • Early stage groups, which are associated with a good risk, include T0I0S0.
  • Advanced stage groups, which are associated with a poor risk, include any combination of the TIS system that is not T0I0S0. For example, poor risk groups include T1I0S0, T1I1S0, T1I0S1, T1I1S0, T0I1S0, T1I1S1, etc. Thus, any poor risk feature in the TIS staging system places a patient into the poor risk category overall.
References

References

  1. ↑ Kaposi Sarcoma Treatment–for health professionals. National Cancer Institute (2015) http://www.cancer.gov/types/soft-tissue-sarcoma/hp/kaposi-treatment-pdq#section/_15 Accessed on January, 20 2015
  2. ↑ Krown SE, Metroka C, Wernz JC (1989). “Kaposi’s sarcoma in the acquired immune deficiency syndrome: a proposal for uniform evaluation, response, and staging criteria. AIDS Clinical Trials Group Oncology Committee”. J Clin Oncol. 7 (9): 1201–7. PMID 2671281.
  3. ↑ Krown SE, Testa MA, Huang J (1997). “AIDS-related Kaposi’s sarcoma: prospective validation of the AIDS Clinical Trials Group staging classification. AIDS Clinical Trials Group Oncology Committee”. J Clin Oncol. 15 (9): 3085–92. PMID 9294471.
  4. ↑ Sarcoma- Kaposi Guide. Cancer.Net (2015) http://www.cancer.net/cancer-types/sarcoma-kaposi/risk-factors-and-prevention Accessed on January, 20 2015
  5. ↑ How is Kaposi sarcoma staged? American Cancer Association (2015) http://www.cancer.org/cancer/kaposisarcoma/detailedguide/kaposi-sarcoma-staging Accessed on January, 20 2016

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [3]