Developer site: The content shown here is test data.

MyEClinic
MyEClinic
Health Dictionary AI Health Chat Find an Online Doctor
A serene Zen garden with raked sand and smooth stones, symbolising clarity and calm

Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

Back to skin conditions

List of bestselling drugs

Introduction

The following is a list of the top 200 pharmaceutical products ranked by sales.

Rank 2006 Brand Name(s) Generic Name Sales 2006 (USD millions) Change from 2005 Company(ies) Disease/Medical Use First Approval Date
1 Lipitor Atorvastatin 14,385 7% Pfizer, Astellas Pharma Cholesterol Dec-1996
2 Advair, Seretide Fluticasone + Salmeterol 6,129 12% GlaxoSmithKline Asthma Aug-2000
3 Plavix, Iscover Clopidogrel 6,057 -5% Bristol-Myers Squibb, Sanofi-Aventis Thrombotic events Nov-1997
4 Nexium Esomeprazole 5,182 12% AstraZeneca Gastrointestinal disorders Mar-2000
5 Norvasc Amlodipine 4,866 3% Pfizer Hypertension Jul-1992
6 Remicade Infliximab 4,428 23% Johnson & Johnson, Schering-Plough, Tanabe Rheumatoid arthritis Aug-1998
7 Enbrel Etanercept 4,379 20% Amgen, Wyeth Rheumatoid arthritis Nov-1998
8 Zyprexa Olanzapine 4,364 4% Eli Lilly Schizophrenia Sep-1996
9 Diovan Valsartan 4,223 15% Novartis Hypertension Dec-1996
10 Risperdal Risperidone 4,183 18% Johnson & Johnson Schizophrenia Dec-1993
11 Aranesp Darbepoetin alfa 4,121 26% Amgen Anemia Jun-2001
12 Rituxan, MabThera Rituximab 3,861 16% Roche, Genentech, Biogen Idec, Chugai Pharmaceutical Non-Hodgkin’s lymphoma Nov-1997
13 Effexor Venlafaxine 3,722 8% Wyeth Depression Dec-1993
14 Protonix, Pantozol, Pantoloc Pantoprazole 3,621 4% Wyeth, Altana, Solvay Gastrointestinal disorders Feb-2000
15 Singulair Montelukast 3,579 20% Merck & Co. Asthma Feb-1998
16 Seroquel Quetiapine 3,560 23% AstraZeneca, Astellas Pharma Schizophrenia Sep-1997
17 Prevacid, Takepron Lansoprazole 3,425 3% TAP Pharmaceuticals, Takeda Pharmaceutical Gastrointestinal disorders May-1995
18 Procrit, Eprex Erythropoietin 3,180 -4% Johnson & Johnson Anemia Dec-1990
19 Cozaar, Hyzaar Losartan 3,163 4% Merck & Co. Hypertension Apr-1995
20 Fosamax Alendronate 3,134 -2% Merck & Co. Osteoporosis Sep-1995
21 Herceptin Trastuzumab 3,134 83% Roche, Genentech, Chugai Pharmaceutical Breast cancer Sep-1998
22 Lovenox, Clexane Enoxaparin 3,059 14% Sanofi-Aventis Deep-vein thrombosis Mar-1993
23 Avandia, Avandamet, Avandaryl Rosiglitazone 3,043 26% GlaxoSmithKline Type 2 diabetes May-1999
24 Actos Pioglitazone 2,880 25% Takeda Pharmaceutical, Eli Lilly Type 2 diabetes Jul-1999
25 Zocor Simvastatin 2,803 -36% Merck & Co. Cholesterol Dec-1991
26 Copaxone Glatiramer 2,757 19% Teva Pharmaceutical Industries, Sanofi-Aventis Multiple sclerosis Dec-1996
27 AcipHex, Pariet Rabeprazole 2,729 -4% Eisai, Johnson & Johnson Gastrointestinal disorders Aug-1999
28 Neulasta Filgrastim 2,710 18% Amgen Neutropenia Jan-2002
29 Lexapro, Cipralex Escitalopram 2,696 16% Forest Laboratories, H. Lundbeck Major depressive disorder Aug-2002
30 Gleevec, Glivec Imatinib 2,554 18% Novartis Leukemia May-2001
31 Ambien, Stilnox Zolpidem 2,545 33% Sanofi-Aventis Insomnia Dec-1992
32 Aricept Donepezil 2,519 24% Eisai, Pfizer Alzheimer’s disease Nov-1996
33 Epogen Erythropoietin 2,511 2% Amgen Anemia Jun-1989
34 Zyrtec, Cirrus Cetirizine 2,377 9% Pfizer, UCB, Daiichi Sankyo Allergic rhinitis Dec-1995
35 Avapro, Aprovel, Avalide Irbesartan 2,372 13% Sanofi-Aventis, Bristol-Myers Squibb Hypertension Sep-1997
36 Avastin Bevacizumab 2,364 78% Roche, Genentech Colorectal cancer Feb-2004
37 Taxotere Docetaxel 2,201 9% Sanofi-Aventis Cancer Oct-1995
38 Eloxatin, Eloxatine Oxaliplatin 2,127 8% Sanofi-Aventis Colorectal cancer Aug-2002
39 Zoloft Sertraline 2,110 -35% Pfizer Depression Dec-1991
40 Tamiflu Oseltamivir 2,096 69% Roche, Chugai Pharmaceutical Influenza Oct-1999
41 Lantus Insulin analog 2,093 37% Sanofi-Aventis Type 2 diabetes and type 1 diabetes Apr-2000
42 Crestor Rosuvastatin 2,049 61% AstraZeneca, Shionogi Cholesterol Nov-2002
43 Humira Adalimumab 2,044 46% Abbott Laboratories Rheumatoid arthritis Dec-2002
44 Celebrex Celecoxib 2,039 18% Pfizer Osteoarthritis and rheumatoid arthritis Dec-1998
45 Topamax Topiramate 2,027 21% Johnson & Johnson Seizures Dec-1996
46 Prevnar vaccine 1,961 30% Wyeth Pneumococcal disease Feb-2000
47 Vytorin Ezetimibe + Simvastatin 1,955 90% Merck & Co., Schering-Plough Cholesterol Jul-2004
48 Zetia Ezetimibe 1,929 38% Merck & Co., Schering-Plough Cholesterol Oct-2002
49 Wellbutrin Bupropion 1,926 26% GlaxoSmithKline, Biovail Depression Aug-2003
50 Abilify Aripiprazole 1,900 1% Otsuka Pharmaceutical, Bristol-Myers Squibb Schizophrenia Nov-2002
51 Lamictal Lamotrigine 1,843 19% GlaxoSmithKline Seizures Dec-1994
52 Toprol, Seloken Metoprolol 1,795 3% AstraZeneca Hypertension Jan-1992
53 NeoRecormon, Epogin Erythropoietin 1,777 -1% Roche, Chugai Pharmaceutical Anemia Jul-1997
54 Atacand, Blopress Candesartan 1,768 8% Takeda Pharmaceutical, AstraZeneca Hypertension Oct-1997
55 Spiriva Tiotropium 1,735 45% Boehringer Ingelheim Chronic obstructive pulmonary disease Apr-2002
56 Avonex Interferon beta-1a 1,707 11% Biogen Idec Multiple sclerosis May-1996
57 Viagra Sildenafil 1,657 1% Pfizer Erectile dysfunction Mar-1998
58 Micardis Telmisartan 1,645 35% Boehringer Ingelheim, Astellas Pharma Hypertension Nov-1998
59 Actonel Risedronate 1,619 -4% Procter & Gamble, Sanofi-Aventis Osteoporosis Mar-1998
60 Lupron, Leuplin Leuprolide 1,579 1% Takeda Pharmaceutical, TAP Pharmaceuticals Prostate cancer Jan-1989
61 TriCor, Lipanthyl Fenofibrate 1,567 38% Abbott Laboratories, Solvay Cholesterol Feb-1998
62 Zofran Ondansetron 1,567 3% GlaxoSmithKline Nausea and vomiting Dec-1992
63 Valtrex Valaciclovir 1,563 24% GlaxoSmithKline Herpes Jun-1995
64 Levaquin, Floxin Levofloxacin 1,530 3% Johnson & Johnson Bacterial infections Dec-1996
65 Arimidex Anastrozole 1,508 28% AstraZeneca Breast cancer Dec-1995
66 Prograf Tacrolimus 1,499 20% Astellas Pharma Transplant rejection Apr-1993
67 CellCept Mycophenolate mofetil 1,470 8% Roche, Chugai Pharmaceutical Transplant rejection May-1995
68 Xalatan, Xalacom Latanoprost 1,453 6% Pfizer Intraocular pressure Jun-1996
69 Rebif Interferon beta-1a 1,452 14% Serono Multiple sclerosis Feb-1998
70 Coreg Carvedilol 1,441 38% GlaxoSmithKline Hypertension Sep-1995
71 Gemzar Gemcitabine 1,408 5% Eli Lilly Cancer May-1996
72 Prilosec, Losec Omeprazole 1,371 -17% AstraZeneca Gastrointestinal disorders Sep-1989
73 Benicar, Olmetec Olmesartan 1,370 73% Daiichi Sankyo, Forest Laboratories Hypertension Apr-2002
74 Lotrel Amlodipine + Benazepril 1,352 26% Novartis Hypertension Jun-1999
75 Cymbalta Duloxetine 1,316 94% Eli Lilly Depressive disorder Aug-2004
76 Imitrex, Imigran Sumatriptan 1,315 4% GlaxoSmithKline Migraine Dec-1992
77 Depakote Valproate 1,308 19% Abbott Laboratories Seizures Mar-1983
78 Humalog Insulin analog 1,300 8% Eli Lilly Diabetes Apr-1996
79 Duragesic Fentanyl 1,295 -18% Johnson & Johnson Pain Aug-1990
80 Pulmicort Budesonide 1,292 11% AstraZeneca Asthma Jun-1997
81 Zometa Zoledronate 1,283 5% Novartis Hypercalcemia Aug-2000
82 Betaseron, Betaferon Interferon beta-1b 1,245 14% Schering AG Multiple sclerosis Jul-1993
83 Delix, Tritace Ramipril 1,227 -3% Sanofi-Aventis Hypertension Jul-2000
84 Flovent, Flixotide Fluticasone 1,219 5% GlaxoSmithKline Asthma Mar-1996
85 Neupogen Filgrastim 1,213 0% Amgen Neutropenia Feb-1991
86 Casodex Bicalutamide 1,206 7% AstraZeneca Prostate cancer Oct-1995
87 Pravachol Pravastatin 1,197 -47% Bristol-Myers Squibb Cholesterol Oct-1991
88 Truvada Tenofovir + Emtricitabine 1,194 110% Gilead Sciences HIV infection Aug-2004
89 Symbicort Budesonide + Formoterol 1,184 18% AstraZeneca Asthma Aug-2000
90 Pegasys Pegylated interferon alfa-2a 1,171 5% Roche, Chugai Pharmaceutical Hepatitis C Jun-2002
91 Evista Raloxifene 1,159 4% Eli Lilly, Chugai Pharmaceutical Osteoporosis Dec-1997
92 Flomax Tamsulosin 1,158 28% Boehringer Ingelheim Benign prostatic hypertrophy Oct-1997
93 Lyrica Pregabalin 1,156 297% Pfizer Neuropathic pain Jul-2004
94 Paxil, Seroxat Paroxetine 1,147 3% GlaxoSmithKline Depression Dec-1992
95 Kaletra Lopinavir 1,135 13% Abbott Laboratories HIV infection Mar-2001
96 Detrol Tolterodine 1,100 11% Pfizer Overactive bladder Mar-1998
97 Harnal Tamsulosin 1,085 -8% Astellas Pharma Benign prostatic hypertrophy Jul-1992
98 Erbitux Cetuximab 1,075 56% Bristol-Myers Squibb, Merck KGaA Colorectal cancer Feb-2004
99 Synagis Palivizumab 1,065 -9% MedImmune Respiratory syncytial virus Jun-1998
100 Augmentin Co-amoxiclav 1,055 -13% GlaxoSmithKline Bacterial infections Aug-1984
101 Premarin, Prempro, Premphase Estrogen 1,051 16% Wyeth Menopausal symptoms Nov-1995
102 Ortho contraceptives Estrogen + Progesterone 1,016 -11% Johnson & Johnson Contraception Apr-1984
103 Zoladex Goserelin 1,008 0% AstraZeneca Prostate cancer Dec-1989
104 Cerezyme Imiglucerase 1,007 8% Genzyme Gaucher disease Apr-1991
105 Cravit Levofloxacin 1,002 2% Daiichi Sankyo, Santen Pharmaceutical Bacterial infections Jun-1909
106 Yasmin Drospirenone 998 36% Schering AG Prevention of pregnancy Aug-2000
107 Kogenate Recombinant factor VIII 989 19% Bayer Hemophilia Feb-1993
108 Botox Botulin toxin 982 18% Allergan Cervical dystonia Dec-1989
109 Lamisil Terbinafine 978 -14% Novartis Fungal infections Dec-1992
110 Combivir Lamivudine + Zidovudine 977 -8% GlaxoSmithKline HIV infection Sep-1997
111 Zosyn, Tazocin Piperacillin 972 9% Wyeth Bacterial infections Oct-1993
112 Cialis Tadalafil 971 30% Lilly, Lilly Icos Erectile dysfunction Nov-2002
113 Keppra Levetiracetam 956 36% UCB Seizures Nov-1999
114 NovoSeven Factor VII 948 11% Novo Nordisk Bleeding due to hemophilia Feb-1996
115 Infanrix, Pediarix vaccine 945 21% GlaxoSmithKline Diphtheria, tetanus, and pertussis Jan-1996
116 Nasonex Mometasone 944 28% Schering-Plough Allergic rhinitis Oct-1997
117 Reyataz Atazanavir 931 34% Bristol-Myers Squibb HIV infection Jan-2003
118 Concerta Methylphenidate 930 20% Johnson & Johnson Attention-deficit hyperactivity disorder Aug-2000
119 Humulin Recombinant human insulin 925 -8% Eli Lilly Diabetes Oct-1982
120 Neoral, Sandimmun Ciclosporin 918 -4% Novartis Transplant rejection Jul-1995
121 Sandostatin Somatostatin 915 2% Novartis Acromegaly Oct-1988
122 Camptosar Irinotecan 903 -1% Pfizer Colorectal cancer Jun-1996
123 Engerix-B, Havrix, Twinrix vaccine 886 10% GlaxoSmithKline Hepatitis Aug-1989
124 Allegra, Telfast Fexofenadine 864 -49% Sanofi-Aventis Allergic rhinitis Jul-1996
125 Adderall Amphetamine 864 18% Shire Pharmaceuticals Attention-deficit hyperactivity disorder Oct-2001
126 Combivent Ipratropium + Salbutamol 843 20% Boehringer Ingelheim Chronic obstructive pulmonary disease Oct-1996
127 Peg-Intron Pegylated interferon alfa-2b 837 11% Schering-Plough Hepatitis C May-2000
128 Adalat Nifedipine 825 0% Bayer Hypertension Nov-1985
129 Avelox, Avalox Moxifloxacin 822 17% Bayer, Schering-Plough, Shionogi Bacterial infections Dec-1999
130 Mobic Meloxicam 818 -66% Boehringer Ingelheim, Daiichi Sankyo Osteoarthritis and rheumatoid arthritis Feb-1996
131 Biaxin Clarithromycin 816 -23% Abbott Laboratories Bacterial infections Oct-1991
132 Mevalotin Pravastatin 799 -35% Daiichi Sankyo Cholesterol Jun-1909
133 Ultane, Sevorane Sevoflurane 799 -9% Abbott Laboratories Anesthesia Jun-1995
134 Genotropin Somatropin 795 -2% Pfizer Growth failure Aug-1995
135 Sustiva Efavirenz 791 16% Bristol-Myers Squibb HIV infection Sep-1998
136 Zyvox Linezolid 782 27% Pfizer Bacterial infections Apr-2000
137 Xeloda Capecitabine 775 22% Roche, Chugai Pharmaceutical Cancer Jun-1909
138 Geodon, Zeldox Ziprasidone 758 29% Pfizer Schizophrenia Feb-2001
139 Cipro, Ciprobay Ciprofloxacin 755 -6% Bayer, Schering-Plough Bacterial infections Oct-1987
140 Provigil Modafinil 735 43% Cephalon Sleepiness Dec-1998
141 Lescol Fluvastatin 725 -5% Novartis Cholesterol Dec-1993
142 Clarinex, Aerius Desloratadine 722 12% Schering-Plough Allergic rhinitis Dec-2001
143 Femara Letrozole 722 35% Novartis, Chugai Pharmaceutical Breast cancer Jul-1997
144 Trileptal Oxcarbazepine 721 17% Novartis Seizures Nov-1999
145 Tracleer Bosentan 717 42% Actelion Pulmonary arterial hypertension Nov-2001
146 Primaxin Imipenem + Cilastatin 705 -5% Merck & Co. Bacterial infections Nov-1985
147 Temodar Temozolomide 703 20% Schering-Plough Anaplastic astrocytoma Aug-1999
148 Trusopt, Cosopt Dorzolamide 697 13% Merck & Co. Intraocular pressure Dec-1994
149 Voltaren Diclofenac 690 0% Novartis Osteoarthritis and rheumatoid arthritis Jul-1998
150 Viread Tenofovir 689 -12% Gilead Sciences HIV infection Oct-2001
151 Sifrol Pramipexole 673 23% Boehringer Ingelheim Parkinson’s disease Oct-1997
152 Namenda Memantine 660 30% Forest Laboratories Alzheimer disease Oct-2003
153 Altace Ramipril 653 18% King Pharmaceuticals Cardiovascular events Jan-1991
154 Byetta Exenatide 649 464% Amylin Pharmaceuticals, Eli Lilly Type 2 diabetes Apr-2005
155 Tarceva Erlotinib 649 110% Roche, Genentech Non-small cell lung cancer Nov-2004
156 Zithromax, Zmax Azithromycin 638 -68% Pfizer Bacterial infections Nov-1991
157 Omnicef Cefdinir 637 29% Abbott Laboratories Bacterial infections Dec-1997
158 Proscar Finasteride 619 -16% Merck & Co. Benign prostatic hypertrophy Jun-1992
159 Alimta Pemetrexed 612 32% Eli Lilly Non-small cell lung cancer Feb-2004
160 Merrem Meropenem 604 20% AstraZeneca Bacterial infections Jun-1996
161 Forteo Teriparatide 594 53% Eli Lilly Osteoporosis Nov-2002
162 Strattera Atomoxetine 579 5% Eli Lilly Attention-deficit hyperactivity disorder Nov-2002
163 Actiq Fentanyl 578 40% Cephalon Cancer pain Nov-1998
164 Flonase, Flixonase Fluticasone 575 -52% GlaxoSmithKline Allergic rhinitis Oct-1994
165 Amaryl Glimepiride 567 -33% Sanofi-Aventis Type 2 diabetes Nov-1995
166 Lidoderm Lidocaine 567 35% Endo Pharmaceuticals Pain Mar-1999
167 Lunesta Eszopiclone 567 72% Sepracor Insomnia Dec-2004
168 Boniva, Bonviva Ibandronate 565 454% Roche, GlaxoSmithKline Osteoporosis Mar-2005
169 Taxol Paclitaxel 563 -25% Bristol-Myers Squibb Cancer Dec-1992
170 Zelnorm, Zelmac Tegaserod 561 34% Novartis Irritable bowel syndrome Mar-2002
171 Renagel Sevelamer 559 23% Genzyme, Roche, Chugai Pharmaceutical Hyperphosphatemia Oct-1998
172 Norditropin Human growth hormone 557 19% Novo Nordisk Growth hormone deficiency Jun-1909
173 Xopenex Levalbuterol 555 29% Sepracor Bronchospasm Mar-1999
174 Xenical Orlistat 553 9% Roche Obesity Jul-1998
175 Vasotec, Vaseretic Enalapril 547 -12% Merck & Co. Hypertension Dec-1985
176 Serevent Salmeterol 538 -10% GlaxoSmithKline Asthma Feb-1994
177 Cardura Doxazosin 538 -8% Pfizer Hypertension Nov-1990
178 Synthroid Levothyroxine 534 -4% Abbott Laboratories Hypothyroidism May-1909
179 Gonal-f Follitropin alfa 533 -3% Serono Infertility Oct-1995
180 Gaster Famotidine 532 -10% Astellas Pharma Gastrointestinal disorders Jun-1909
181 Cancidas Caspofungin 530 -7% Merck & Co. Fungal infections Jan-2001
182 Exelon Rivastigmine 525 12% Novartis Alzheimer’s disease May-1998
183 Vfend Voriconazole 515 30% Pfizer Fungal infections Mar-2002
184 Amlodin Amlodipine 506 4% Dainippon Sumitomo Hypertension, angina pectoris n/a
185 Niaspan Niacin 498 13% Kos Pharmaceuticals Cholesterol Jul-1997
186 Neurontin Gabapentin 496 -22% Pfizer Seizures Dec-1993
187 Trizivir Abacavir + Lamivudine + Zidovudine 496 -10% GlaxoSmithKline HIV infection Nov-2000
188 Requip Ropinirole 496 74% GlaxoSmithKline Parkinson disease Sep-1997
189 Follistim, Puregon Follitropin beta 482 8% Akzo Nobel Infertility Sep-1997
190 Basen Voglibose 476 -13% Takeda Pharmaceutical Hyperglycemia Jun-1909
191 Levitra Vardenafil 474 19% Bayer, GlaxoSmithKline Erectile dysfunction Mar-2003
192 Glucophage Metformin 459 -16% Merck KGaA, Bristol-Myers Squibb Type 2 diabetes Dec-1994
193 Concor Bisoprolol 455 4% Merck KGaA Hypertension Jul-1992
194 Epzicom, Kixeva Abacavir + Lamivudine 446 107% GlaxoSmithKline HIV infection Aug-2004
195 Xatral Alfuzosin 443 8% Sanofi-Aventis Benign prostatic hypertrophy Jan-2000
196 Diflucan Fluconazole 435 -13% Pfizer Fungal infections Jan-1990
197 Thalomid Thalidomide 433 12% Celgene Erythema nodosum leprosum Jul-1998
198 Zantac Ranitidine 429 -18% GlaxoSmithKline Gastrointestinal disorders Jun-1983
199 Xolair Omalizumab 429 32% Roche, Genentech Asthma Jun-2003
200 Claritin Loratadine 418 -5% Schering-Plough, Shionogi Allergic rhinitis Apr-1993

Source: MedAdNews 200 – World’s Best-Selling Medicines, MedAdNews, July 2007