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Lopinavir ritonavir indications and usage

Introduction

Lopinavir ritonavir
KALETRA ® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages
Indications and Usage

Indications and Usage

KALETRA is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients (14 days and older).

The following points should be considered when initiating therapy with KALETRA:

  • The use of other active agents with KALETRA is associated with a greater likelihood of treatment response [see Microbiology (12.4) and Clinical Studies (14)].
  • Genotypic or phenotypic testing and/or treatment history should guide the use of KALETRA [see Microbiology (12.4)]. The number of baseline lopinavir resistance-associated substitutions affects the virologic response to KALETRA [see Microbiology].[1]
References

References

Adapted from the FDA Package Insert.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]