Lymphogranuloma venereum history and symptoms

The most common symptom of primary LGV is a painless papule or ulcer. Secondary LGV is characterized by painful inguinal and/or femoral lymphadenopathy, or Iliac and/or perirectal lymphadenopathy in patients with rectal exposure. Proctolcolits may also develop at this stage. Tertiary LGV symptoms include Lymphatic and rectal fibrosis, genital elephantiasis, esthiomene (chronic ulcerative disease of vulva), edema, tenesmus and rectal discharge. LGV may spread systemically and cause the following symptoms: fever, chills, malaise, myalgia, arthralgia, arthritis, hepatitis or perihepatitis, and pneumonitis.

• Painless papule or ulcer
• May be unnoticed by patient
• Proctitis in patients with rectal exposure^[1]

• Painful inguinal and/or femoral lymphadenopathy, usually unilateral^[2]

• Lymphadenopathy may be characterized as fluctuant, suppurative buboes or nonsuppurative abscesses

• Iliac and/or perirectal lymphadenopathy in patients with rectal exposure
• Hemorrhagic proctocolitis
• Lower abdominal or low-back pain^[3]

• Lymphatic and rectal fibrosis^[4]
• Lymphorroids (hemorrhoid-like swellings of lymphatics)
• Chronic edema
• Genital elephantiasis^[1]
• Esthiomene (chronic ulcerative disease of vulva)
• Frozen pelvis syndrome^[5]
• Tenesmus
• Bloody purulent rectal discharge
• Rectal pain
• Hyperplasia of intestinal and perirectal lymphatic tissue^[2]

• Fever
• Chills
• Malaise
• Myalgia
• Arthralgia
• Arthritis
• Hepatitis or perihepatitis
• Pneumonitis
• Cardiac involvment (rare)
• Aseptic meningitis (rare)
• Ocular inflammatory disease (rare)^[2]

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