
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions β written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Lymphogranuloma venereum history and symptoms
Introduction
Overview
Overview
The most common symptom of primary LGV is a painless papule or ulcer. Secondary LGV is characterized by painful inguinal and/or femoral lymphadenopathy, or Iliac and/or perirectal lymphadenopathy in patients with rectal exposure. Proctolcolits may also develop at this stage. Tertiary LGV symptoms include Lymphatic and rectal fibrosis, genital elephantiasis, esthiomene (chronic ulcerative disease of vulva), edema, tenesmus and rectal discharge. LGV may spread systemically and cause the following symptoms: fever, chills, malaise, myalgia, arthralgia, arthritis, hepatitis or perihepatitis, and pneumonitis.
Symptoms
Symptoms
Primary LGV
Secondary LGV
- Painful inguinal and/or femoral lymphadenopathy, usually unilateral[2]
- Iliac and/or perirectal lymphadenopathy in patients with rectal exposure
- Hemorrhagic proctocolitis
- Lower abdominal or low-back pain[3]
Tertiary LGV
- Lymphatic and rectal fibrosis[4]
- Lymphorroids (hemorrhoid-like swellings of lymphatics)
- Chronic edema
- Genital elephantiasis[1]
- Esthiomene (chronic ulcerative disease of vulva)
- Frozen pelvis syndrome[5]
- Tenesmus
- Bloody purulent rectal discharge
- Rectal pain
- Hyperplasia of intestinal and perirectal lymphatic tissue[2]
Systemic Symptoms
- Fever
- Chills
- Malaise
- Myalgia
- Arthralgia
- Arthritis
- Hepatitis or perihepatitis
- Pneumonitis
- Cardiac involvment (rare)
- Aseptic meningitis (rare)
- Ocular inflammatory disease (rare)[2]
References
References
- β 1.0 1.1 Mabey, D (2002). “Lymphogranuloma venereum”. Sexually Transmitted Infections. 78 (2): 90β92. doi:10.1136/sti.78.2.90. ISSNΒ 1368-4973.
- β 2.0 2.1 2.2 Ceovic R, Gulin SJ (2015). “Lymphogranuloma venereum: diagnostic and treatment challenges”. Infect Drug Resist. 8: 39β47. doi:10.2147/IDR.S57540. PMCΒ 4381887. PMIDΒ 25870512.
- β de Vries HJ, Zingoni A, White JA, Ross JD, Kreuter A (2013). “2013 European Guideline on the management of proctitis, proctocolitis and enteritis caused by sexually transmissible pathogens”. Int J STD AIDS. 25 (7): 465β474. doi:10.1177/0956462413516100. PMIDΒ 24352129.
- β Lynch CM, Felder TL, Schwandt RA, Shashy RG (1999). “Lymphogranuloma venereum presenting as a rectovaginal fistula”. Infect Dis Obstet Gynecol. 7 (4): 199β201. doi:10.1155/S1064744999000344. PMCΒ 1784745. PMIDΒ 10449269.
- β Van der Bij AK, Spaargaren J, MorrΓ© SA, Fennema HS, Mindel A, Coutinho RA; et al. (2006). “Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men: a retrospective case-control study”. Clin Infect Dis. 42 (2): 186β94. doi:10.1086/498904. PMIDΒ 16355328.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.
