Male contraceptive
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The only forms of male contraceptives currently available to men are condoms, the withdrawal method, and vasectomy. Other forms of male contraception are in various stages of research and development.
References
Historical Perspective
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Abandoned research
- Gossypol, derived from cotton seeds, was used in trials by the Chinese government for about fifteen years. While it was found to be a reliable contraceptive, it has serious health effects, and ten to twenty percent of users become permanently sterile. Research on it as a temporary contraceptive has been abandoned.
- Zavesca (aka Miglustat or NB-DNJ) is a drug approved for treatment of several rare lipid storage disorder diseases. In mice, it provided effective and fully reversible contraception. But it seems this effect was only true for several genetically related strains of laboratory mice. Zavesca showed no contraceptive effect in other mammals.[1]
References
- ↑ Amory JK, Muller CH, Page ST, Leifke E, Pagel ER, Bhandari A, Subramanyam B, Bone W, Radlmaier A, Bremner WJ. Miglustat has no apparent effect on spermatogenesis in normal men. Human Reproduction advance access 25 October 2006.
Pathophysiology
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References
Causes
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References
Differentiating Male contraceptive from other Diseases
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References
Epidemiology and Demographics
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References
Risk Factors
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References
Natural History, Complications and Prognosis
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References
Diagnosis
Diagnosis
History and Symptoms | Physical Examination | Laboratory Findings | Other Imaging Findings | Other Diagnostic Studies
Treatment
Treatment
Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies
References
References
Related Chapters
Related Chapters
- Male Contraception Information Project
- UCSB’s Sex Info page on male contraception
- MaleContraceptives.org has a summary of experimental male contraceptive methods.
- Male contraceptive trial has 100% success in New Scientist, 6 October 2003.
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