
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Medullary thyroid cancer historical perspective
Introduction
Overview
Overview
Medullary thyroid cancer was first discovered by Dr. John Beach Hazard, an American pathologist, in 1959.
Historical Perspective
Historical Perspective
- In 1959, Dr. Hazard described medullary (solid) thyroid carcinoma.[1][2]
- In 1961, Dr. Sipple described a combination of a pheochromocytoma, medullary thyroid carcinoma, and parathyroid adenoma.
- In 1966, Dr. Williams proposed the C-cells as the origin of medullary thyroid cancer.[3]
- In 1966, Dr. Pearse proposed the name C-cell indicating their function in calcitonin secrestion.[4]
- In 1978, Dr. Cameron suggested that medullary thyroid cancer produces thyrocalcitonin from parafollicular cells.
References
References
- ↑ HAZARD JB, HAWK WA, CRILE G (1959). “Medullary (solid) carcinoma of the thyroid; a clinicopathologic entity”. J. Clin. Endocrinol. Metab. 19 (1): 152–61. doi:10.1210/jcem-19-1-152. PMID 13620740.
- ↑ Dionigi G, Bianchi V, Rovera F, et al. (2007). “Medullary thyroid carcinoma: surgical treatment advances”. Expert Rev Anticancer Ther. 7 (6): 877–85. doi:10.1586/14737140.7.6.877. PMID 17555398.
- ↑ Williams, E. D. (1966). “Histogenesis of medullary carcinoma of the thyroid”. Journal of Clinical Pathology. 19 (2): 114–118. doi:10.1136/jcp.19.2.114. ISSN 0021-9746.
- ↑ “The cytochemistry of the thyroid C cells and their relationship to calcitonin”. Proceedings of the Royal Society of London. Series B. Biological Sciences. 164 (996): 478–487. 1966. doi:10.1098/rspb.1966.0044. ISSN 2053-9193.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
