Mixed connective tissue disease secondary prevention

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]

Overview

In MCTD effective measures for the secondary prevention of Raynaud’s disease include vasodilator therapies (such as calcium channel blockers), preventive approaches like avoidance of cold temperatures, smoking, and sympathomimetic agents and use of warm and protection techniques of fingers. Current strategies include Bosentan (endothelin receptor antagonist) as the recommended medication for the prevention of new digital ulcers.

Secondary Prevention

In MCTD effective measures for the secondary prevention of Raynaud’s disease include:^[1]
- Vasodilator therapies (such as calcium channel blockers)
- Preventive approaches like avoidance of cold temperatures, smoking, and sympathomimetic agents
- Use of warm and protection techniques of fingers
Current strategies include Bosentan (endothelin receptor antagonist) as the recommended medication for the prevention of new digital ulcers.

References

↑ Ortega-Hernandez OD, Shoenfeld Y (February 2012). “Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment”. Best Pract Res Clin Rheumatol. 26 (1): 61–72. doi:10.1016/j.berh.2012.01.009. PMID 22424193.

Overview