Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Multiple myeloma other imaging findings
Introduction
Overview
Overview
Positron emission tomography (PET) scan may be diagnostic of multiple myeloma. Findings on PET scan suggestive of multiple myeloma include uptake of the F18-FDG molecule by lesions of bone lysis seen on PET-CT scan.
Positron Emission Tomography Scan
Positron Emission Tomography Scan
- Positron emission tomography (PET) scan is a highly sensitive and specific diagnostic tool for diagnosing multiple myeloma.[1][2][3][4]
- Uptake of the F18-FDG molecule by lesions of multiple myeloma corresponds to areas of bone lysis seen on PET–CT scan.[5][3]
- PET scan is superior to either CT scan or X-ray for diagnosis of lytic lesions of multiple myeloma.[1][2][4]
- PET scan is useful in the detection of cancer spread to distant lymph nodes.[1][2]
- PET scan assess for spleen involvement more readily than other imaging modalities.
- The use of PET scan has led to earlier diagnosis of multiple myeloma and increased the accuracy of therapy response assessment.[6]
- PET scan has still not been employed as a standard of care by the International Myeloma Working Group.[6]
References
References
- ↑ 1.0 1.1 1.2 Shortt CP, Gleeson TG, Breen KA, McHugh J, O’Connell MJ, O’Gorman PJ; et al. (2009). “Whole-Body MRI versus PET in assessment of multiple myeloma disease activity”. AJR Am J Roentgenol. 192 (4): 980–6. doi:10.2214/AJR.08.1633. PMID 19304704.
- ↑ 2.0 2.1 2.2 Agarwal A, Chirindel A, Shah BA, Subramaniam RM (2013). “Evolving role of FDG PET/CT in multiple myeloma imaging and management”. AJR Am J Roentgenol. 200 (4): 884–90. doi:10.2214/AJR.12.9653. PMID 23521465.
- ↑ 3.0 3.1 Gerecke C, Fuhrmann S, Strifler S, Schmidt-Hieber M, Einsele H, Knop S (July 2016). “The Diagnosis and Treatment of Multiple Myeloma”. Dtsch Arztebl Int. 113 (27–28): 470–6. doi:10.3238/arztebl.2016.0470. PMC 4973001. PMID 27476706.
- ↑ 4.0 4.1 Diagnosing multiple myeloma. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/diagnosis/?region=mb#blood_chem Accessed on September, 20th 2015
- ↑ Multiple myeloma. Radiopaedia (2015)http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
- ↑ 6.0 6.1 Dimopoulos M, Terpos E, Comenzo RL, Tosi P, Beksac M, Sezer O; et al. (2009). “International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma”. Leukemia. 23 (9): 1545–56. doi:10.1038/leu.2009.89. PMID 19421229.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2] Shyam Patel [3]