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Nalfurafine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Overview

Nalfurafine (INN and USAN;[1] also known as AC-820, TRK-820; trade name Remitch) is a κ-opioid receptor agonist marketed as a treatment for uremic pruritus in people undergoing hemodialysis.[2]

As of January 2010, it is also being investigated for the treatment of pruritus in patients with chronic liver disease.[3]

References

References

  1. Statement on a Nonproprietary Name adopted by the USAN Council
  2. “AC-820”. Acologix. 2009.
  3. Clinical trial number NCT00638495 for “Phase II Study of TRK-820 Soft Capsules — Intractable Pruritus in Patients With Chronic Liver Disease” at ClinicalTrials.gov

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