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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions β€” written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Nalfurafine

Introduction

Overview

Overview

Nalfurafine (INN and USAN;[1] also known as AC-820, TRK-820; trade name Remitch) is a ΞΊ-opioid receptor agonist marketed as a treatment for uremic pruritus in people undergoing hemodialysis.[2]

As of JanuaryΒ 2010, it is also being investigated for the treatment of pruritus in patients with chronic liver disease.[3]

References

References

  1. ↑ Statement on a Nonproprietary Name adopted by the USAN Council
  2. ↑ “AC-820”. Acologix. 2009.
  3. ↑ Clinical trial number NCT00638495 for “Phase II Study of TRK-820 Soft Capsules β€” Intractable Pruritus in Patients With Chronic Liver Disease” at ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]