Effective preventative measures for parotitis include the mumps vaccine, maintaining personal hygiene and limiting proximal contact with mumps or staphyloccocus aureus infected individuals, limiting sexual contact with HIV-infected individuals and using condoms during sexual intercourse, and the Bacillus Calmette-Guérin vaccine to prevent extrapulmonary tuberculosis. Preventative measures for obstruction-based parotitis include reducing risk factors for salivary gland stones and parotid gland neoplasia.

• Administering the mumps vaccine
  • 78% effective at a single dose; 88% effective with two doses administered with at least 28 days in between.^{_Vaccination_|_CDC-1|[1]}
• Personal hygiene and limiting contact exposure:^{_Transmission_|_CDC-2|[2]}
  • Washing hands frequently.
  • Avoiding fluid transmission with mumps patients.
  • Avoiding respiratory droplets from coughing mumps patients.
• Limiting contact with children between 9 months and 15 years old.^{_Vaccination_|_CDC-1|[1]}
• Limiting sexual contact with HIV-infected individuals and using condoms.^{_HIV_Basics_|_HIV/AIDS_|_CDC-3|[3]}
• Administering the Bacillus Calmette-Guérin vaccine to prevent tuberculosis.^[4]

• Reducing risk factors associated with salivary gland stones or neoplasia:
  • Limiting alcohol consumption.
  • Reducing tobacco consumption and smoking.
  • Avoiding harmful inhalants, such as pesticides.