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Health Dictionary

Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.

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Portal hypertension classification

Introduction

Overview

Overview

Based on the etiology, portal hypertension may be classified as pre-hepatic, intra-hepatic, and post-hepatic. Intra-hepatic portal hypertension classified into pre-sinusoidal, sinusoidal, and post-sinusoidal disorders. Based on the functional impairment in the liver, portal hypertension may be classified as cirrhotic and non-cirrhotic.

Classification

Classification

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Portal Hypertension classification
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Functional
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Etiology
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Cirrhotic
 
 
 
Non-cirrhotic
 
 
 
Without any underlying cause
 
 
Pre-hepatic portal hypertension
 
 
 
 
Intra-hepatic portal hypertension
 
 
 
 
Post-hepatic portal hypertension
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Idiopathic portal hypertension
 
 
 
 
 
Pre-sinusoidal disorders
 
Sinusoidal
disorders
 
Post-sinusoidal disorders
 
 
 
 
Group Wedged hepatic venous pressure (WHVP) Free hepatic vein pressure (FHVP) Hepatic vein pressure gradient (HVPG) Cause
Pre-hepatic portal hypertension Normal Normal Normal
Intra-hepatic portal hypertension[3] Pre-sinusoidal disorders Normal Normal Normal
Sinusoidal disorders Elevated Elevated Elevated
Post-sinusoidal disorders Elevated Normal Elevated
Post-hepatic portal hypertension[4] Elevated Elevated Normal
  • Increased post-hepatic vessels resistance

 Idiopathic portal hypertension (IPH)

References

References

  1. ↑ Grammatikopoulos, Tassos; McKiernan, Patrick James; Dhawan, Anil (2017). “Portal hypertension and its management in children”. Archives of Disease in Childhood: archdischild-2015–310022. doi:10.1136/archdischild-2015-310022. ISSN 0003-9888.
  2. ↑ Králík J, Neoral C (1992). “[Rational therapy of prehepatic portal hypertension]”. Rozhl Chir (in Czech). 71 (10): 513–22. PMID 1475714.
  3. ↑ Bertocchini A, Falappa P, Grimaldi C, Bolla G, Monti L, de Ville de Goyet J (2014). “Intrahepatic portal venous systems in children with noncirrhotic prehepatic portal hypertension: anatomy and clinical relevance”. J. Pediatr. Surg. 49 (8): 1268–75. doi:10.1016/j.jpedsurg.2013.10.029. PMID 25092088.
  4. ↑ Abd El-Hamid N, Taylor RM, Marinello D, Mufti GJ, Patel R, Mieli-Vergani G, Davenport M, Dhawan A (2008). “Aetiology and management of extrahepatic portal vein obstruction in children: King’s College Hospital experience”. J. Pediatr. Gastroenterol. Nutr. 47 (5): 630–4. doi:10.1097/MPG.0b013e31817b6eea. PMID 18955865.
  5. ↑ 5.0 5.1 Nakanuma, Yasuni; Tsuneyama, Koichi; Makoto, Ohbu; Katayanagi, Kazuyoshi (2001). “Pathology and Pathogenesis of Idiopathic Portal Hypertension with an Emphasis on the Liver”. Pathology – Research and Practice. 197 (2): 65–76. doi:10.1078/0344-0338-5710012. ISSN 0344-0338.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]