Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Portal vein thrombosis laboratory findings
Introduction
Overview
Overview
Laboratory findings is usually normal among patients with portal vein thrombosis. In patients with cirrhosis, laboratory findings may demonstrate an elevated bilirubin, low platelet count, prolonged international normalized ratio (INR), or renal insufficiency.
Laboratory Findings
Laboratory Findings
- Laboratory findings of portal vein thrombosis will be normal or quite normal, unless there is coexistence of a liver disease.
- Although, coagulation factors levels could be moderately decreased, while D-dimer level is usually increased.
- In some patients laboratory findings may show moderate increase in serum aminotransferases.[1][2][3]
- In patients with cirrhosis, laboratory findings may demonstrate an elevated bilirubin, low platelet count, prolonged international normalized ratio (INR), or renal insufficiency.
- Blood cultures of septic portal vein are often positive for Bacteroides fragilis or Escherichia coli, also other pathogens have been cultured.[4]
References
References
- ↑ Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). “Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment”. World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
- ↑ Condat B, Valla D (2006). “Nonmalignant portal vein thrombosis in adults”. Nat Clin Pract Gastroenterol Hepatol. 3 (9): 505–15. doi:10.1038/ncpgasthep0577. PMID 16951667.
- ↑ Zhang WW, Churchill S, Churchill P (1989). “Developmental regulation of D-beta-hydroxybutyrate dehydrogenase in rat liver and brain”. FEBS Lett. 256 (1–2): 71–4. PMID 2806552.
- ↑ Plemmons RM, Dooley DP, Longfield RN (1995). “Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era”. Clin. Infect. Dis. 21 (5): 1114–20. PMID 8589130.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]