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Portmanteau inhibitor

Introduction

A portmanteau inhibitor is a drug which is a combination of two drug molecules, each of which is itself a type of inhibitor. The term was coined in 2007 by University of Minnesota researchers who designed and synthesized a combination HIV Reverse transcriptase inhibitor and an Integrase inhibitor.[1][2][3]

Footnotes

  1. ↑ “U of M researchers announce advance in treatment of HIV”. 25 July 2007. Unknown parameter |accessed-date= ignored (help)
  2. ↑ “Researchers Discover New Method To Combat HIV”. 25 July 2007. Unknown parameter |accessed-date= ignored (help)
  3. ↑ Zhengqiang Wang, Eric M. Bennett, Daniel J. Wilson, Christine Salomon, and Robert Vince (2007). “Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and Integrase”. Journal of Medicinal Chemistry. 50 (15): 3416-3419. PMID 17608468.

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