Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Postpartum thyroiditis causes
Introduction
Overview
Overview
Postpartum thyroiditis (PPT) is a type of subacute lymphocytic thyroiditis that occurs due to autoimmune response towards thyroid gland in postpartum period, miscarriage, or abortion. PPT is an autoimmune disorder. PPT is caused by a mutation in the G-allele of CD60 CTLA-4 gene, HLA-DR3, HLA-DR4, and HLA-DR5 gene. To review details about various risk factors that contribute to the development of PPT, click here.
Causes
Causes
Postpartum thyroiditis (PPT) is a type of subacute lymphocytic thyroiditis that occurs due to autoimmune response towards thyroid gland in postpartum period, miscarriage, or abortion.[1]
Genetic Causes
Postpartum thyroiditis (PPT) is caused by a mutation in the G-allele of the following:[2]
- CD60 CTLA-4 gene
- HLA-DR3 gene
- HLA-DR4 gene
- HLA-DR5 gene
Causes in Alphabetical Order
Following is a list of the various causes of the postpartum thyroididtis in alphabetical order:
- CD60 CTLA-4 gene
- HLA-DR3 gene
- HLA-DR4 gene
- HLA-DR5 gene
References
References
- ↑ Premawardhana LD, Parkes AB, Ammari F, John R, Darke C, Adams H; et al. (2000). “Postpartum thyroiditis and long-term thyroid status: prognostic influence of thyroid peroxidase antibodies and ultrasound echogenicity”. J Clin Endocrinol Metab. 85 (1): 71–5. doi:10.1210/jcem.85.1.6227. PMID 10634366.
- ↑ Stagnaro-Green A (2012). “Approach to the patient with postpartum thyroiditis”. J Clin Endocrinol Metab. 97 (2): 334–42. doi:10.1210/jc.2011-2576. PMID 22312089.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]