Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Primary biliary cirrhosis causes
Introduction
Overview
Overview
The cause of primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing primary biliary cirrhosis. Few environmental factors such as cigarette smoking, infections and chemical exposure have also known to play a role in causing primary biliary cirrhosis.
Causes
Causes
- The cause of primary biliary cirrhosis has not been identified. However, it is thought that hyper-functioning immune system attributed to genetic predisposition is thought to have a role in causing primary biliary cirrhosis.[1][2][3]
- Few environmental factors such as cigarette smoking, infections and chemical exposure are also known to play a role in causing primary biliary cirrhosis.[1][2][3]
- To learn more about the risk factors for the development of primary biliary cirrhosis, click here.
References
References
- ↑ 1.0 1.1 Carey EJ, Ali AH, Lindor KD (2015). “Primary biliary cirrhosis”. Lancet. 386 (10003): 1565–75. doi:10.1016/S0140-6736(15)00154-3. PMID 26364546.
- ↑ 2.0 2.1 Selmi C, Bowlus CL, Gershwin ME, Coppel RL (2011). “Primary biliary cirrhosis”. Lancet. 377 (9777): 1600–9. doi:10.1016/S0140-6736(10)61965-4. PMID 21529926.
- ↑ 3.0 3.1 Juran BD, Lazaridis KN (2014). “Environmental factors in primary biliary cirrhosis”. Semin Liver Dis. 34 (3): 265–72. doi:10.1055/s-0034-1383726. PMC 4232304. PMID 25057950.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]