Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Reynolds syndrome
Introduction
Please help WikiDoc by adding more content here. It’s easy! Click here to learn about editing.
Overview
Overview
Reynolds syndrome is a rare autoimmune disease, consisting of the combination of primary biliary cirrhosis and progressive systemic sclerosis. In some patients this syndrome has also been associated with Sjögren’s syndrome and hemolytic anemia. Typical clinical features include jaundice, elevated blood levels of alkaline phosphatase, calcinosis cutis, telangiectasias, and pruritus. Raynaud’s phenomenon may be an early clinical feature. The syndrome, a special case of scleroderma, is named after the American physician, Telfer B. Reynolds, MD (1921-2004), who first described it. He is also known for creating one of the world’s first hepatology programs at the University of Southern California.
References
References
- T. B. Reynolds, E. K. Denison, H. D. Frank, F. L. Lieberman, R. L. Peters: Primary biliary cirrhosis with scleroderma, Raynaud’s phenomenon and telangiectasia. New syndrome. American Journal of Medicine, New York, 1971, 50 (3): 302-312.
- Volker Stadie, Johannes Wohlrab, Wolfgang Christian Marsch: The Reynolds Syndrome – a Rare Combination of Two Autoimmune Diseases. Medizinische Klinik, München, 2002, 97 (1): 40-43.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]