Rhinoscleroma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Rhinoscleroma is a chronic granulomatous bacterial disease of the nose that can sometimes infect the upper respiratory tract. It most commonly affects the nasal cavity—the nose is involved in 95-100 per cent of cases—however, it can also affect the nasopharynx, larynx, trachea, and bronchi.

Slightly more females than males are affected and patients are usually 10 to 30 years of age. Rhinoscleroma is considered a tropical disease and is mostly endemic to Africa and Central America, less common in the United States.

Rhinoscleroma is not lethal in nature and is responsive to Tetracycline or Ciprofloxacin. However, if left untreated the disease can lead to sepsis, hemorrhage or other chronic conditions that can be fatal.

Rhinoscleroma is not lethal in nature and is responsive to Tetracycline or Ciprofloxacin.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Hans von Hebra (1847–1902) wrote the classical description of the disease in a paper published in the January 1870 issue of the Wiener Medizinische Wochenschrift. Hans von Hebra was the son of Czech born dermatologist Ferdinand Ritter von Hebra (1816–1880), founder of the New Vienna School of Dermatology. He was assisted by M. Kohn who provided much of the histology for the paper. M. Kohn is the birth name of Moritz Kaposi (1837–1902). In 1876, Mikulicz contributed to the microscopic histology. In 1882, Anton Von Frisch (1849–1917) discovered the gram-negative bacillus which causes the disease. Klebsiella rhinoscleromatis is sometimes referred to as the “Frisch bacillus,” named for Anton von Frisch.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Klebsiella rhinoscleromatis is a subspecies of Klebsiella pneumoniae— a gram-negative, encapsulated, nonmotile, rod-shaped bacillus (diplobacillus), member of the Enterobacteriaceae family. It is sometimes referred to as the “Frisch bacillus,” named for Anton von Frisch who identified the organism in 1882. It is contracted directly by droplets or by contamination of material that is subsequently inhaled.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Slightly more females than males are affected and patients are usually 10 to 30 years of age. Rhinoscleroma is considered a tropical disease and is mostly endemic to Africa and Central America, less common in the United States.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please help WikiDoc by adding more content here. It’s easy! Click here to learn about editing.

Rhinoscleroma is not lethal in nature and is responsive to Tetracycline or Ciprofloxacin. However, if left untreated the disease can lead to sepsis, hemorrhage or other chronic conditions that can be fatal.

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