Sinusoidal obstruction syndrome historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Husnain Shaukat, M.D [2]

Overview

Hepatic veno-occlusive disease or sinusoidal obstruction syndrome was first described in 1905 as endophelibitis of the terminal hepatic veins. Ionizing radiations as a cause of sinusoidal obstruction syndrome was identified in the 1960’s and bone marrow transplant in the 1970’s. However, sinusoidal obstruction syndrome or hepatic veno-occlusive disease was a well-established concept by the mid-1960’s.

Historical Perspective

Endophlebitis in the terminal hepatic venule was first described by a pathologist from Prague in 1905.^[1]
In the 1960s, studies on the effects of hepatic vasculature by ionizing radiations were reported. ^[2]^[3]
The concept of sinusoidal obstruction syndrome induced by either chemical or radiation toxicity was well established by mid-1960s as a separate entity from Budd-Chiari syndrome.^[4]
The bone marrow transplant became the therapeutic option during the 1960’s and reports of sinusoidal obstruction syndrome or hepatic veno-occlusive disease emerged in the 1970’s.^[5]

References

↑ Fan CQ, Crawford JM (2014). “Sinusoidal obstruction syndrome (hepatic veno-occlusive disease)”. J Clin Exp Hepatol. 4 (4): 332–46. doi:10.1016/j.jceh.2014.10.002. PMC 4298625. PMID 25755580.
↑ Dormoy A, Urlacher A, Tongio MM (1990). “A nucleotide substitution in a Bg1 II site is responsible for the RFLP discrimination between DPw4 and DPa”. Tissue Antigens. 36 (3): 129–35. PMID 1980552.
↑ STIRLING GA, BRAS B, URQUHART AE (1962). “The early lesions in veno-occlusive disease of the liver”. Arch. Dis. Child. 37: 535–8. PMC 2012933. PMID 13984193.
↑ GIBSON JB (1960). “Chiari’s disease and the Budd-Chiari syndrome”. J Pathol Bacteriol. 79: 381–401. PMID 13827970.
↑ Harper G (1992). “Relief work: don’t forget Somalia. Interview by Charlotte Alderman”. Nurs Stand. 7 (1): 18–9. PMID 1419702.

Overview