Squamous cell carcinoma of the skin historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]
Overview
Overview
Reports of non-melanoma cancer date back to biblical times. Percival Pott was the first person to report the malignant nature of squamous cell carcinoma in adolescent British chimney sweeps. This was the first described occupational and exposure-related risk factor for squamous cell carcinoma. Later, other occupational and exposure associations were reported when there were reported incidences of squamous cell carcinoma in mule spinners, and it was therefore called mule spinner’s disease. French surgeon Jean-Nicholas Marjolin, in 1828, first described this carcinoma arising in traumatic scars, and subsequently any squamous cell carcinoma associated with burns was termed ”Marjolin’s ulcer”.
Historical Perspective
Historical Perspective
Reports of non-melanoma cancer date back to biblical times. Percival Pott was the first person to report the malignant nature of squamous cell carcinoma in adolescent British chimney sweeps. This was the first described occupational and exposure-related risk factor for squamous cell carcinoma. Later, other occupational and exposure associations were reported when there were reported incidences of squamous cell carcinoma in mule spinners, and it was therefore called mule spinner’s disease.[1] French surgeon Jean-Nicholas Marjolin, in 1828, first described this carcinoma arising in traumatic scars, and subsequently any squamous cell carcinoma associated with burns was termed ”Marjolin’s ulcer”.[2]
References
References
- ↑ Castiglione FM, Selikowitz SM, Dimond RL (March 1985). “Mule spinner’s disease”. Arch Dermatol. 121 (3): 370–2. PMID 3977358.
- ↑ Pekarek, Brian; Buck, Stacie; Osher, Lawrence (2011). “A Comprehensive Review on Marjolin’s Ulcers: Diagnosis and Treatment”. The Journal of the American College of Certified Wound Specialists. 3 (3): 60–64. doi:10.1016/j.jcws.2012.04.001. ISSN 1876-4983.
Looking for the patient version?
© 2026 MyEClinic – IFTM Institut für Telematik in der Medizin GmbH