
Health Dictionary
Reliable, easy-to-read patient information on common medical conditions — written in plain language, free of jargon, and grounded in current evidence. Browse the most frequent diagnoses, understand what they mean for everyday life, and learn which steps and questions help you have a focused conversation with your doctor.
Syphilis other imaging findings
Introduction
Overview
Overview
Other imaging findings of syphilis include novel PET/CT technology, multimodal ophthalmologic imaging, bone scintigraphy, and angiography. PET/CT is a novel imaging study which portrays 18F-Fluorodeoxyglucose (FDG) uptake enhanced regions superimposed on cross sectional CT images. Multimodal ophthalmologic imaging combines ophthalmoscopy with spectral domain optical coherence tomography (SD-OCT) to produce high definition imaging of the posterior chamber of the eye. Bone scintigraphy allows clinicians to visualize bone uptake of Technetium-99 (T-99m) using x-ray technology. These imaging findings allow clinicians to detect syphilitic manifestations involving the bone, retina, heart, lungs, and lymph nodes.[1][2][2][3][4][5][6]
Other imaging studies
Other imaging studies
Other imaging findings of syphilis include novel PET/CT technology, multimodal ophthalmologic imaging, bone scintigraphy, and angiography. These imaging findings allow clinicians to detect syphilitic manifestations involving the bone, retina, heart, lungs, and lymph nodes.
PET/CT (FDG Uptake)
- Bone
- Increased 18F-Fluorodeoxyglucose (FDG) uptake and osseous destruction[1]
- Pulmonary
- Increased FDG uptake in multiple pulmonary nodules (mimicking pulmonary metastasis)[2]
- Other
- Increased FDG uptake in lymph nodes (generalized lymphadenopathy in secondary syphilis)[3]
Bone Scintigraphy
Multimodal Ophthalmologic Imaging
References
References
- ↑ 1.0 1.1 Wang X, Yin J, Chen X (2011). “Syphilitic bone destruction on FDG PET/CT”. Clin Nucl Med. 36 (7): 616–8. doi:10.1097/RLU.0b013e318219ac62. PMID 21637078.
- ↑ 2.0 2.1 2.2 Kim HJ, Seon HJ, Shin HH, Choi YD (2011). “Case report: Pulmonary syphilis mimicking pulmonary hematogenous metastases on chest CT and integrated PET/CT”. Indian J Radiol Imaging. 21 (1): 34–7. doi:10.4103/0971-3026.76052. PMC 3056368. PMID 21431031.
- ↑ 3.0 3.1 Kim JM, Lee SM, Bae SB, Lee JS, Kim SY (2016). “The role of PET/CT in diagnosing generalized lymphadenopathy in asymptomatic secondary syphilis”. Hell J Nucl Med. 19 (1): 60–2. doi:10.1967/s002449910340. PMID 26929943.
- ↑ 4.0 4.1 Naraghi AM, Salonen DC, Bloom JA, Becker EJ (2010). “Magnetic resonance imaging features of osseous manifestations of early acquired syphilis”. Skeletal Radiol. 39 (3): 305–9. doi:10.1007/s00256-009-0806-7. PMID 19795120.
- ↑ 5.0 5.1 5.2 5.3 Curi AL, Sarraf D, Cunningham ET (2015). “MULTIMODAL IMAGING OF SYPHILITIC MULTIFOCAL RETINITIS”. Retin Cases Brief Rep. 9 (4): 277–80. doi:10.1097/ICB.0000000000000186. PMID 26237137.
- ↑ 6.0 6.1 6.2 Sekine Y, Yashiro S, O’hira A, Yoshida N, Morinaga M, Nagashima N; et al. (2015). “[Multimodal imaging of a case of acute syphilitic posterior placoid chorioretinitis]”. Nippon Ganka Gakkai Zasshi. 119 (4): 266–72. PMID 25980046.
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2], Tarek Nafee, M.D. [3]
