Poikilocytosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Poikilocytosis refers to the presence in the blood of poikilocytes. Poikilocytes are abnormally shaped red blood cells as seen on a blood film. Rather than being seen as a sign of any one disease, poikilocytosis is a rather general condition. There may, however be a predominance of one particular type of abnormally shaped red cells, some of which may indicate possible presence of a specific disease or disorder. [2]

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Abnormal red blood cells are seen in a wide range of conditions, so poikilocytosis is not specific. However, specific types of poikilocytes may be seen in particular disease states and/or disorders.

1. Acanthocytes or Spur/Spike cells
2. Codocytes or Target cells
3. Echinocytes and Burr cells
4. Elliptocytes and Ovalocytes
5. Spherocytes
6. Stomatocytes or Mouth cells

1. Dacrocytes or Teardrop Cells
2. Keratocytes
3. Microspherocytes and Pyropoikilocytes
4. Schistocytes
5. Semilunar bodies

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