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Undifferentiated connective tissue disease medical therapy

Introduction

Overview

Overview

The pharmacologic medical therapy is recommended based on the rheumatic disease pattern manifested by the patient such as methotrexate in those exhibiting arthritis and dermatitis. Supportive therapy includes; avoiding cold exposure in those experiencing Raynaud’s phenomenon, avoiding sun in photosensitivity, non-steroidal anti-inflammatory drugs for pain control, sunscreen used for photosensitivity, and emollients for dry skin and rash.

Medical Therapy

Medical Therapy

Routine measures

Supportive therapy

Arthritis and dermatitis

  • Oral regimen
    • Preferred regimen (1): Methotrexate 7.5 mg PO q24h for 6 months (not used for CNS symptoms or serositis)[1]
      • Dose can be gradually increased to 13.6 mg after 6 months
References

References

  1. ↑ Wise CM, Vuyyuru S, Roberts WN (June 1996). “Methotrexate in nonrenal lupus and undifferentiated connective tissue disease–a review of 36 patients”. J. Rheumatol. 23 (6): 1005–10. PMID 8782131.

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]